| Cellular component | cytoplasm - GO:0005737; cullin-ring ubiquitin ligase complex - GO:0031461; nucleus - GO:0005634; intracellular organelle part - GO:0044446; cytoplasmic part - GO:0044444; nucleoplasm - GO:0005654; organelle part - GO:0044422; intracellular organelle - GO:0043229; cul4-ring e3 ubiquitin ligase complex - GO:0080008; membrane-bounded organelle - GO:0043227; endosome - GO:0005768; cell part - GO:0044464; macromolecular complex - GO:0032991; cul4a-ring e3 ubiquitin ligase complex - GO:0031464; intracellular membrane-bounded organelle - GO:0043231; cytosol - GO:0005829; ubiquitin ligase complex - GO:0000151; protein complex - GO:0043234; cellular_component - GO:0005575; organelle - GO:0043226; intracellular part - GO:0044424; transferase complex - GO:1990234; catalytic complex - GO:1902494; nuclear part - GO:0044428; Cul4A-RING E3 ubiquitin ligase complex - GO:0031464; |
| Molecular function | enzyme regulator activity - GO:0030234; protein serine/threonine kinase inhibitor activity - GO:0030291; kinase inhibitor activity - GO:0019210; peptidase activator activity involved in apoptotic process - GO:0016505; heat shock protein binding - GO:0031072; protein kinase inhibitor activity - GO:0004860; cyclin-dependent protein serine/threonine kinase inhibitor activity - GO:0004861; macromolecular complex binding - GO:0044877; transforming growth factor beta receptor; cytoplasmic mediator activity - GO:0005072; protein kinase regulator activity - GO:0019887; cyclin-dependent protein serine/threonine kinase regulator activity - GO:0016538; protein phosphatase binding - GO:0019903; protein complex binding - GO:0032403; kinase regulator activity - GO:0019207; Hsp70 protein binding - GO:0030544; protein kinase binding - GO:0019901; molecular_function - GO:0003674; cysteine-type endopeptidase regulator activity involved in apoptotic process - GO:0043028; cyclin binding - GO:0030332; chaperone binding - GO:0051087; molecular function regulator - GO:0098772; molecular transducer activity - GO:0060089; enzyme binding - GO:0019899; peptidase regulator activity - GO:0061134; phosphatase binding - GO:0019902; receptor signaling protein activity - GO:0005057; signal transducer activity - GO:0004871; cysteine-type endopeptidase activator activity involved in apoptotic process - GO:0008656; protein binding - GO:0005515; peptidase activator activity - GO:0016504; enzyme activator activity - GO:0008047; hsp70 protein binding - GO:0030544; enzyme inhibitor activity - GO:0004857; binding - GO:0005488; |
| Biological process | cellular response to metal ion - GO:0071248; regulation of gene expression - GO:0010468; protein processing - GO:0016485; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process - GO:0043280; response to oxygen levels - GO:0070482; metabolic process - GO:0008152; response to organonitrogen compound - GO:0010243; regulation of cell death - GO:0010941; signal transduction involved in cell cycle checkpoint - GO:0072395; negative regulation of cellular biosynthetic process - GO:0031327; negative regulation of developmental process - GO:0051093; negative regulation of epithelial cell proliferation involved in prostate gland development - GO:0060770; negative regulation of reproductive process - GO:2000242; regulation of protein serine/threonine kinase activity - GO:0071900; cellular response to organic cyclic compound - GO:0071407; regulation of multicellular organismal development - GO:2000026; regulation of response to stimulus - GO:0048583; negative regulation of mitotic cell cycle - GO:0045930; positive regulation of cellular process - GO:0048522; placenta development - GO:0001890; regulation of macromolecule metabolic process - GO:0060255; negative regulation of transcription; dna-templated - GO:0045892; response to drug - GO:0042493; negative regulation of cell cycle phase transition - GO:1901988; negative regulation of cell proliferation - GO:0008285; regulation of cell cycle g1/s phase transition - GO:1902806; regulation of cellular process - GO:0050794; regulation of macromolecule biosynthetic process - GO:0010556; negative regulation of protein modification process - GO:0031400; signal transduction involved in mitotic cell cycle checkpoint - GO:0072413; regulation of microtubule polymerization - GO:0031113; regulation of microtubule-based process - GO:0032886; cellular response to stress - GO:0033554; regulation of immune system process - GO:0002682; regulation of protein phosphorylation - GO:0001932; signal transduction - GO:0007165; mitotic cell cycle - GO:0000278; sensory perception of sound - GO:0007605; metal ion transport - GO:0030001; immune response-regulating signaling pathway - GO:0002764; negative regulation of cell cycle g1/s phase transition - GO:1902807; positive regulation of biological process - GO:0048518; signal transduction in response to dna damage - GO:0042770; regulation of protein catabolic process - GO:0042176; negative regulation of mitotic cell cycle phase transition - GO:1901991; response to cadmium ion - GO:0046686; response to amino acid - GO:0043200; regulation of organelle organization - GO:0033043; positive regulation of cell cycle arrest - GO:0071158; response to acid chemical - GO:0001101; primary metabolic process - GO:0044238; regulation of cell growth - GO:0001558; regulation of nucleic acid-templated transcription - GO:1903506; response to glucose - GO:0009749; fc-epsilon receptor signaling pathway - GO:0038095; response to monosaccharide - GO:0034284; signal transduction involved in mitotic dna damage checkpoint - GO:1902402; cell cycle - GO:0007049; regulation of exit from mitosis - GO:0007096; cellular response to antibiotic - GO:0071236; regulation of rna metabolic process - GO:0051252; response to carbohydrate - GO:0009743; positive regulation of microtubule polymerization or depolymerization - GO:0031112; cellular response to organic substance - GO:0071310; regulation of kinase activity - GO:0043549; response to peptide - GO:1901652; transport - GO:0006810; regulation of nucleobase-containing compound metabolic process - GO:0019219; fibroblast growth factor receptor signaling pathway - GO:0008543; positive regulation of cellular component organization - GO:0051130; death - GO:0016265; response to metal ion - GO:0010038; erbb signaling pathway - GO:0038127; dna damage response; signal transduction by p53 class mediator resulting in cell cycle arrest - GO:0006977; regulation of reproductive process - GO:2000241; regulation of rna biosynthetic process - GO:2001141; regulation of hydrolase activity - GO:0051336; cellular response to dna damage stimulus - GO:0006974; regulation of transcription; dna-templated - GO:0006355; response to hypoxia - GO:0001666; negative regulation of g1/s transition of mitotic cell cycle - GO:2000134; cell cycle arrest - GO:0007050; organic substance metabolic process - GO:0071704; response to decreased oxygen levels - GO:0036293; single-organism developmental process - GO:0044767; negative regulation of biosynthetic process - GO:0009890; phosphatidylinositol-mediated signaling - GO:0048015; regulation of phosphorylation - GO:0042325; regulation of programmed cell death - GO:0043067; regulation of cytoskeleton organization - GO:0051493; cellular process - GO:0009987; positive regulation of proteolysis - GO:0045862; signal transduction involved in dna integrity checkpoint - GO:0072401; positive regulation of cell proliferation - GO:0008284; cell cycle g1/s phase transition - GO:0044843; regulation of lens fiber cell differentiation - GO:1902746; negative regulation of protein kinase activity - GO:0006469; single-organism localization - GO:1902578; positive regulation of molecular function - GO:0044093; response to lithium ion - GO:0010226; negative regulation of nitrogen compound metabolic process - GO:0051172; response to chemical - GO:0042221; positive regulation of programmed cell death - GO:0043068; positive regulation of cytoskeleton organization - GO:0051495; response to stimulus - GO:0050896; developmental process - GO:0032502; response to hexose - GO:0009746; response to estradiol - GO:0032355; monovalent inorganic cation transport - GO:0015672; negative regulation of transcription; DNA-templated - GO:0045892; cellular response to inorganic substance - GO:0071241; regulation of cellular component organization - GO:0051128; regulation of cellular protein metabolic process - GO:0032268; response to estrogen - GO:0043627; negative regulation of gene expression - GO:0010629; negative regulation of molecular function - GO:0044092; immune response-regulating cell surface receptor signaling pathway - GO:0002768; regulation of phosphate metabolic process - GO:0019220; response to organic cyclic compound - GO:0014070; epidermal growth factor receptor signaling pathway - GO:0007173; establishment of localization - GO:0051234; regulation of multicellular organismal process - GO:0051239; regulation of immune response - GO:0050776; cellular response to toxic substance - GO:0097237; response to oxygen-containing compound - GO:1901700; regulation of mitotic cell cycle - GO:0007346; cation transport - GO:0006812; positive regulation of endopeptidase activity - GO:0010950; cell death - GO:0008219; response to nitrogen compound - GO:1901698; ion transport - GO:0006811; cellular response to stimulus - GO:0051716; negative regulation of nucleic acid-templated transcription - GO:1903507; signal transduction involved in mitotic dna integrity checkpoint - GO:1902403; regulation of biological process - GO:0050789; cellular response to lithium ion - GO:0071285; protein metabolic process - GO:0019538; positive regulation of hydrolase activity - GO:0051345; positive regulation of cyclin-dependent protein serine/threonine kinase activity - GO:0045737; positive regulation of apoptotic process - GO:0043065; response to toxic substance - GO:0009636; neurotrophin signaling pathway - GO:0038179; neurotrophin trk receptor signaling pathway - GO:0048011; regulation of primary metabolic process - GO:0080090; enzyme linked receptor protein signaling pathway - GO:0007167; negative regulation of programmed cell death - GO:0043069; regulation of g1/s transition of mitotic cell cycle - GO:2000045; cell cycle phase transition - GO:0044770; regulation of cysteine-type endopeptidase activity involved in apoptotic process - GO:0043281; intracellular signal transduction - GO:0035556; positive regulation of organelle organization - GO:0010638; regulation of nitrogen compound metabolic process - GO:0051171; regulation of protein modification process - GO:0031399; regulation of cell cycle process - GO:0010564; regulation of cellular biosynthetic process - GO:0031326; positive regulation of cysteine-type endopeptidase activity - GO:2001056; dna damage response; signal transduction by p53 class mediator - GO:0030330; regulation of cellular component biogenesis - GO:0044087; positive regulation of microtubule polymerization - GO:0031116; regulation of metabolic process - GO:0019222; potassium ion transport - GO:0006813; G1/S transition of mitotic cell cycle - GO:0000082; signal transduction involved in dna damage checkpoint - GO:0072422; heart development - GO:0007507; positive regulation of cell cycle process - GO:0090068; negative regulation of protein serine/threonine kinase activity - GO:0071901; positive regulation of catabolic process - GO:0009896; negative regulation of epithelial cell proliferation - GO:0050680; negative regulation of cellular process - GO:0048523; DNA damage response; signal transduction by p53 class mediator resulting in cell cycle arrest - GO:0006977; regulation of growth - GO:0040008; localization - GO:0051179; multicellular organismal process - GO:0032501; negative regulation of catalytic activity - GO:0043086; anatomical structure development - GO:0048856; negative regulation of cyclin-dependent protein serine/threonine kinase activity - GO:0045736; regulation of phosphorus metabolic process - GO:0051174; positive regulation of catalytic activity - GO:0043085; negative regulation of phosphorus metabolic process - GO:0010563; regulation of cell proliferation - GO:0042127; immune system process - GO:0002376; response to hormone - GO:0009725; negative regulation of rna metabolic process - GO:0051253; regulation of microtubule polymerization or depolymerization - GO:0031110; positive regulation of cell death - GO:0010942; regulation of epithelial cell proliferation involved in prostate gland development - GO:0060768; intracellular signal transduction involved in g1 dna damage checkpoint - GO:1902400; negative regulation of nucleobase-containing compound metabolic process - GO:0045934; single-organism process - GO:0044699; negative regulation of phosphorylation - GO:0042326; response to steroid hormone - GO:0048545; positive regulation of protein complex assembly - GO:0031334; regulation of developmental process - GO:0050793; regulation of cell cycle - GO:0051726; macromolecule metabolic process - GO:0043170; regulation of catabolic process - GO:0009894; regulation of mitotic cell cycle phase transition - GO:1901990; response to antibiotic - GO:0046677; regulation of catalytic activity - GO:0050790; negative regulation of macromolecule biosynthetic process - GO:0010558; positive regulation of protein polymerization - GO:0032273; regulation of protein polymerization - GO:0032271; negative regulation of cellular macromolecule biosynthetic process - GO:2000113; negative regulation of phosphate metabolic process - GO:0045936; Notch signaling pathway - GO:0007219; response to lipid - GO:0033993; response to inorganic substance - GO:0010035; regulation of proteolysis - GO:0030162; negative regulation of apoptotic process - GO:0043066; positive regulation of macromolecule metabolic process - GO:0010604; negative regulation of protein phosphorylation - GO:0001933; regulation of protein metabolic process - GO:0051246; regulation of transferase activity - GO:0051338; negative regulation of kinase activity - GO:0033673; response to alcohol - GO:0097305; innate immune response - GO:0045087; regulation of microtubule cytoskeleton organization - GO:0070507; regulation of cysteine-type endopeptidase activity - GO:2000116; regulation of cellular component movement - GO:0051270; single-multicellular organism process - GO:0044707; mitotic cell cycle phase transition - GO:0044772; negative regulation of cell cycle - GO:0045786; system process - GO:0003008; response to abiotic stimulus - GO:0009628; regulation of protein complex assembly - GO:0043254; negative regulation of cardiac muscle tissue regeneration - GO:1905179; positive regulation of metabolic process - GO:0009893; negative regulation of growth - GO:0045926; negative regulation of multicellular organismal process - GO:0051241; regulation of cellular metabolic process - GO:0031323; positive regulation of cellular component biogenesis - GO:0044089; programmed cell death - GO:0012501; cell surface receptor signaling pathway - GO:0007166; regulation of biosynthetic process - GO:0009889; defense response - GO:0006952; regulation of localization - GO:0032879; g1/s transition of mitotic cell cycle - GO:0000082; regulation of protein kinase activity - GO:0045859; negative regulation of metabolic process - GO:0009892; regulation of cell cycle phase transition - GO:1901987; regulation of peptidase activity - GO:0052547; positive regulation of cellular protein metabolic process - GO:0032270; positive regulation of protein metabolic process - GO:0051247; negative regulation of protein metabolic process - GO:0051248; negative regulation of biological process - GO:0048519; positive regulation of cellular metabolic process - GO:0031325; cellular response to chemical stimulus - GO:0070887; mitotic cell cycle arrest - GO:0071850; immune response - GO:0006955; mitotic cell cycle process - GO:1903047; response to organic substance - GO:0010033; transmembrane receptor protein tyrosine kinase signaling pathway - GO:0007169; sensory perception - GO:0007600; negative regulation of vascular smooth muscle cell proliferation - GO:1904706; zymogen activation - GO:0031638; activation of cysteine-type endopeptidase activity - GO:0097202; negative regulation of cell cycle process - GO:0010948; regulation of cell cycle arrest - GO:0071156; biological_process - GO:0008150; fc receptor signaling pathway - GO:0038093; signal transduction by p53 class mediator - GO:0072331; negative regulation of cellular component movement - GO:0051271; negative regulation of cell death - GO:0060548; signal transduction involved in mitotic g1 dna damage checkpoint - GO:0072431; response to peptide hormone - GO:0043434; positive regulation of peptidase activity - GO:0010952; regulation of cyclin-dependent protein serine/threonine kinase activity - GO:0000079; negative regulation of cellular metabolic process - GO:0031324; response to endogenous stimulus - GO:0009719; single-organism cellular process - GO:0044763; positive regulation of protein catabolic process - GO:0045732; biological regulation - GO:0065007; sensory perception of mechanical stimulus - GO:0050954; negative regulation of rna biosynthetic process - GO:1902679; positive regulation of cell cycle - GO:0045787; inner ear development - GO:0048839; activation of cysteine-type endopeptidase activity involved in apoptotic process - GO:0006919; negative regulation of cellular protein metabolic process - GO:0032269; inositol lipid-mediated signaling - GO:0048017; regulation of endopeptidase activity - GO:0052548; negative regulation of macromolecule metabolic process - GO:0010605; regulation of cellular macromolecule biosynthetic process - GO:2000112; response to stress - GO:0006950; neurological system process - GO:0050877; negative regulation of cyclin-dependent protein kinase activity - GO:1904030; negative regulation of cell growth - GO:0030308; cell cycle process - GO:0022402; single-organism transport - GO:0044765; autophagic cell death - GO:0048102; regulation of apoptotic process - GO:0042981; negative regulation of transferase activity - GO:0051348; regulation of epithelial cell proliferation - GO:0050678; regulation of molecular function - GO:0065009; |
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