Ontology list
Cellular componentcytosol - GO:0005829; SMAD2-SMAD3 protein complex - GO:0071144; nuclear transcription factor complex - GO:0044798; smad2-smad3 protein complex - GO:0071144; intracellular membrane-bounded organelle - GO:0043231; nuclear chromosome part - GO:0044454; macromolecular complex - GO:0032991; cell part - GO:0044464; membrane-bounded organelle - GO:0043227; organelle part - GO:0044422; intracellular organelle - GO:0043229; nucleoplasm - GO:0005654; cytoplasmic part - GO:0044444; intracellular organelle part - GO:0044446; nucleus - GO:0005634; chromatin - GO:0000785; SMAD protein complex - GO:0071141; cytoplasm - GO:0005737; chromosomal part - GO:0044427; nuclear part - GO:0044428; transcription factor complex - GO:0005667; nuclear chromatin - GO:0000790; smad protein complex - GO:0071141; intracellular part - GO:0044424; organelle - GO:0043226; cellular_component - GO:0005575; protein complex - GO:0043234; rna polymerase ii transcription factor complex - GO:0090575; activin responsive factor complex - GO:0032444;
Molecular functionreceptor binding - GO:0005102; metal ion binding - GO:0046872; co-smad binding - GO:0070410; I-SMAD binding - GO:0070411; RNA polymerase II core promoter proximal region sequence-specific DNA binding - GO:0000978; binding - GO:0005488; transforming growth factor beta receptor binding - GO:0005160; molecular transducer activity - GO:0060089; phosphatase binding - GO:0019902; enzyme binding - GO:0019899; core promoter proximal region dna binding - GO:0001159; heterocyclic compound binding - GO:1901363; ubiquitin protein ligase binding - GO:0031625; double-stranded DNA binding - GO:0003690; dna binding - GO:0003677; co-SMAD binding - GO:0070410; transcription regulatory region dna binding - GO:0044212; sequence-specific dna binding transcription factor activity - GO:0003700; nucleic acid binding transcription factor activity - GO:0001071; double-stranded dna binding - GO:0003690; regulatory region nucleic acid binding - GO:0001067; rna polymerase ii core promoter proximal region sequence-specific dna binding transcription factor activity involved in positive regulation of transcription - GO:0001077; cation binding - GO:0043169; cytokine receptor binding - GO:0005126; tau protein binding - GO:0048156; activating transcription factor binding - GO:0033613; DNA binding - GO:0003677; macromolecular complex binding - GO:0044877; transforming growth factor beta receptor; cytoplasmic mediator activity - GO:0005072; structure-specific dna binding - GO:0043566; type i transforming growth factor beta receptor binding - GO:0034713; r-smad binding - GO:0070412; smad binding - GO:0046332; transforming growth factor beta receptor; pathway-specific cytoplasmic mediator activity - GO:0030618; i-smad binding - GO:0070411; transcriptional activator activity; RNA polymerase II transcription regulatory region sequence-specific binding - GO:0001228; regulatory region dna binding - GO:0000975; R-SMAD binding - GO:0070412; ubiquitin-like protein ligase binding - GO:0044389; SMAD binding - GO:0046332; sequence-specific dna binding rna polymerase ii transcription factor activity - GO:0000981; sequence-specific dna binding - GO:0043565; receptor signaling protein activity - GO:0005057; signal transducer activity - GO:0004871; protein binding - GO:0005515; transcription regulatory region sequence-specific dna binding - GO:0000976; enhancer binding - GO:0035326; core promoter proximal region sequence-specific dna binding - GO:0000987; disordered domain specific binding - GO:0097718; molecular_function - GO:0003674; type I transforming growth factor beta receptor binding - GO:0034713; transcription factor binding - GO:0008134; chromatin binding - GO:0003682; rna polymerase ii core promoter proximal region sequence-specific dna binding - GO:0000978; rna polymerase ii regulatory region dna binding - GO:0001012; protein heterodimerization activity - GO:0046982; nucleic acid binding - GO:0003676; organic cyclic compound binding - GO:0097159; transcription factor activity; sequence-specific DNA binding - GO:0003700; primary miRNA binding - GO:0070878; ion binding - GO:0043167; rna polymerase ii core promoter proximal region sequence-specific dna binding transcription factor activity - GO:0000982; rna polymerase ii transcription regulatory region sequence-specific dna binding transcription factor activity involved in positive regulation of transcription - GO:0001228; RNA polymerase II transcription factor activity; sequence-specific DNA binding - GO:0000981; rna polymerase ii regulatory region sequence-specific dna binding - GO:0000977; protein homodimerization activity - GO:0042803;
Biological processcellular process - GO:0009987; negative regulation of cell communication - GO:0010648; negative regulation of cell differentiation - GO:0045596; single-organism localization - GO:1902578; cellular protein modification process - GO:0006464; negative regulation of nitrogen compound metabolic process - GO:0051172; response to chemical - GO:0042221; regionalization - GO:0003002; single-organism developmental process - GO:0044767; negative regulation of biosynthetic process - GO:0009890; embryonic cranial skeleton morphogenesis - GO:0048701; transcription; dna-templated - GO:0006351; positive regulation of rna metabolic process - GO:0051254; cellular aromatic compound metabolic process - GO:0006725; organic substance biosynthetic process - GO:1901576; regulation of rna biosynthetic process - GO:2001141; positive regulation of cell morphogenesis involved in differentiation - GO:0010770; positive regulation of transcription from rna polymerase ii promoter - GO:0045944; regulation of transcription; dna-templated - GO:0006355; common-partner smad protein phosphorylation - GO:0007182; organic substance metabolic process - GO:0071704; somatic stem cell maintenance - GO:0035019; transport - GO:0006810; regulation of nucleobase-containing compound metabolic process - GO:0019219; positive regulation of cellular component organization - GO:0051130; negative regulation of nucleic acid-templated transcription - GO:1903507; embryonic pattern specification - GO:0009880; positive regulation of mesoderm development - GO:2000382; developmental growth - GO:0048589; regulation of biological process - GO:0050789; protein metabolic process - GO:0019538; formation of primary germ layer - GO:0001704; negative regulation of transforming growth factor beta receptor signaling pathway - GO:0030512; heterocycle metabolic process - GO:0046483; gene expression - GO:0010467; regulation of cell development - GO:0060284; lung development - GO:0030324; response to oxygen-containing compound - GO:1901700; organic cyclic compound metabolic process - GO:1901360; peptide transport - GO:0015833; negative regulation of gene expression - GO:0010629; anatomical structure morphogenesis - GO:0009653; positive regulation of epithelial to mesenchymal transition - GO:0010718; response to organic cyclic compound - GO:0014070; cellular protein complex assembly - GO:0043623; establishment of localization - GO:0051234; regulation of multicellular organismal process - GO:0051239; negative regulation of signal transduction - GO:0009968; primary miRNA processing - GO:0031053; endoderm formation - GO:0001706; response to stimulus - GO:0050896; regulation of anatomical structure morphogenesis - GO:0022603; developmental process - GO:0032502; response to hexose - GO:0009746; response to sterol - GO:0036314; regulation of cellular component organization - GO:0051128; negative regulation of transcription; DNA-templated - GO:0045892; cellular macromolecule metabolic process - GO:0044260; embryonic skeletal system morphogenesis - GO:0048704; positive regulation of signaling - GO:0023056; ncrna processing - GO:0034470; regulation of cellular process - GO:0050794; negative regulation of cell proliferation - GO:0008285; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090100; cellular metabolic process - GO:0044237; regulation of macromolecule biosynthetic process - GO:0010556; positive regulation of transcription; dna-templated - GO:0045893; regulation of nodal signaling pathway involved in determination of left/right asymmetry - GO:1900145; positive regulation of gene expression - GO:0010628; tube development - GO:0035295; embryonic morphogenesis - GO:0048598; cellular component organization or biogenesis - GO:0071840; negative regulation of transcription from rna polymerase ii promoter - GO:0000122; organic substance transport - GO:0071702; regulation of multicellular organismal development - GO:2000026; regulation of response to stimulus - GO:0048583; positive regulation of cellular process - GO:0048522; regulation of activin receptor signaling pathway - GO:0032925; macromolecule modification - GO:0043412; pattern specification process - GO:0007389; regulation of macromolecule metabolic process - GO:0060255; positive regulation of signal transduction - GO:0009967; negative regulation of transcription; dna-templated - GO:0045892; metabolic process - GO:0008152; embryonic organ morphogenesis - GO:0048562; nucleic acid metabolic process - GO:0090304; aromatic compound biosynthetic process - GO:0019438; organ morphogenesis - GO:0009887; hormone transport - GO:0009914; nucleic acid-templated transcription - GO:0097659; smad protein signal transduction - GO:0060395; embryo development ending in birth or egg hatching - GO:0009792; regulation of cell differentiation - GO:0045595; regulation of transcription from rna polymerase ii promoter - GO:0006357; anterior/posterior pattern specification - GO:0009952; organ development - GO:0048513; mesonephric epithelium development - GO:0072163; phosphorylation - GO:0016310; negative regulation of cellular biosynthetic process - GO:0031327; regulation of mesoderm development - GO:2000380; establishment of protein localization - GO:0045184; negative regulation of developmental process - GO:0051093; mesoderm morphogenesis - GO:0048332; paraxial mesoderm morphogenesis - GO:0048340; protein deubiquitination - GO:0016579; regulation of gene expression - GO:0010468; ureteric bud development - GO:0001657; organic cyclic compound biosynthetic process - GO:1901362; macromolecular complex assembly - GO:0065003; regulation of rna metabolic process - GO:0051252; establishment of localization in cell - GO:0051649; response to carbohydrate - GO:0009743; regulation of transforming growth factor beta receptor signaling pathway - GO:0017015; negative regulation of response to stimulus - GO:0048585; SMAD protein signal transduction - GO:0060395; positive regulation of transcription from RNA polymerase II promoter - GO:0045944; positive regulation of multicellular organismal process - GO:0051240; protein complex subunit organization - GO:0071822; transforming growth factor beta receptor signaling pathway - GO:0007179; response to monosaccharide - GO:0034284; regulation of signaling - GO:0023051; positive regulation of cell differentiation - GO:0045597; chordate embryonic development - GO:0043009; skeletal system morphogenesis - GO:0048705; transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0007178; dorsal/ventral axis specification - GO:0009950; amide transport - GO:0042886; transcription initiation from rna polymerase ii promoter - GO:0006367; nitrogen compound metabolic process - GO:0006807; rna biosynthetic process - GO:0032774; signal release - GO:0023061; regulation of nucleic acid-templated transcription - GO:1903506; primary metabolic process - GO:0044238; positive regulation of stem cell differentiation - GO:2000738; response to glucose - GO:0009749; gastrulation - GO:0007369; regulation of cell communication - GO:0010646; in utero embryonic development - GO:0001701; signal transduction - GO:0007165; regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry - GO:1900175; positive regulation of biological process - GO:0048518; cellular nitrogen compound metabolic process - GO:0034641; positive regulation of cellular metabolic process - GO:0031325; positive regulation of nitrogen compound metabolic process - GO:0051173; positive regulation of macromolecule biosynthetic process - GO:0010557; response to organic substance - GO:0010033; positive regulation of cellular biosynthetic process - GO:0031328; regulation of cell morphogenesis - GO:0022604; positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry - GO:1900224; pericardium development - GO:0060039; signal transduction involved in regulation of gene expression - GO:0023019; biological_process - GO:0008150; macromolecular complex subunit organization - GO:0043933; protein modification process - GO:0036211; cellular component organization - GO:0016043; negative regulation of metabolic process - GO:0009892; embryonic foregut morphogenesis - GO:0048617; anatomical structure formation involved in morphogenesis - GO:0048646; tissue development - GO:0009888; response to cholesterol - GO:0070723; cellular protein metabolic process - GO:0044267; ncrna metabolic process - GO:0034660; negative regulation of biological process - GO:0048519; regulation of binding - GO:0051098; positive regulation of activin receptor signaling pathway - GO:0032927; regulation of cellular metabolic process - GO:0031323; negative regulation of signaling - GO:0023057; positive regulation of nucleic acid-templated transcription - GO:1903508; SMAD protein complex assembly - GO:0007183; biosynthetic process - GO:0009058; cell surface receptor signaling pathway - GO:0007166; regulation of biosynthetic process - GO:0009889; phosphate-containing compound metabolic process - GO:0006796; negative regulation of transcription from RNA polymerase II promoter - GO:0000122; cellular nitrogen compound biosynthetic process - GO:0044271; single-multicellular organism process - GO:0044707; cellular component assembly - GO:0022607; dna-templated transcription; initiation - GO:0006352; positive regulation of metabolic process - GO:0009893; regulation of cell morphogenesis involved in differentiation - GO:0010769; secretion by cell - GO:0032940; nodal signaling pathway - GO:0038092; negative regulation of cellular response to transforming growth factor beta stimulus - GO:1903845; cellular developmental process - GO:0048869; regulation of molecular function - GO:0065009; phosphorus metabolic process - GO:0006793; rna metabolic process - GO:0016070; mesenchyme morphogenesis - GO:0072132; positive regulation of nucleobase-containing compound metabolic process - GO:0045935; palate development - GO:0060021; regulation of nodal signaling pathway - GO:1900107; adrenal gland development - GO:0030325; kidney epithelium development - GO:0072073; somatic stem cell population maintenance - GO:0035019; peptide hormone secretion - GO:0030072; single-organism transport - GO:0044765; embryonic axis specification - GO:0000578; biological regulation - GO:0065007; negative regulation of rna biosynthetic process - GO:1902679; positive regulation of cell development - GO:0010720; cellular macromolecular complex assembly - GO:0034622; cellular biosynthetic process - GO:0044249; mesonephric tubule development - GO:0072164; negative regulation of macromolecule metabolic process - GO:0010605; hormone secretion - GO:0046879; regulation of cellular macromolecule biosynthetic process - GO:2000112; peptide secretion - GO:0002790; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090101; regulation of epithelial to mesenchymal transition - GO:0010717; regulation of signal transduction - GO:0009966; protein transport - GO:0015031; nucleobase-containing compound biosynthetic process - GO:0034654; negative regulation of cellular metabolic process - GO:0031324; single-organism cellular process - GO:0044763; smad protein complex assembly - GO:0007183; localization - GO:0051179; multicellular organismal process - GO:0032501; negative regulation of cellular response to growth factor stimulus - GO:0090288; cellular macromolecule biosynthetic process - GO:0034645; regulation of bmp signaling pathway - GO:0030510; regulation of biological quality - GO:0065008; protein complex assembly - GO:0006461; anatomical structure development - GO:0048856; protein phosphorylation - GO:0006468; tissue morphogenesis - GO:0048729; macromolecule biosynthetic process - GO:0009059; regulation of metabolic process - GO:0019222; nitrogen compound transport - GO:0071705; secretion - GO:0046903; growth - GO:0040007; stem cell maintenance - GO:0019827; negative regulation of cellular process - GO:0048523; intracellular signal transduction - GO:0035556; wound healing - GO:0042060; regulation of nitrogen compound metabolic process - GO:0051171; regulation of cellular response to transforming growth factor beta stimulus - GO:1903844; regulation of cellular response to growth factor stimulus - GO:0090287; regulation of cellular biosynthetic process - GO:0031326; macromolecule localization - GO:0033036; embryo development - GO:0009790; protein localization - GO:0008104; regulation of hormone levels - GO:0010817; pancreas development - GO:0031016; mesoderm formation - GO:0001707; post-embryonic development - GO:0009791; cell fate commitment - GO:0045165; positive regulation of bmp signaling pathway - GO:0030513; positive regulation of response to stimulus - GO:0048584; positive regulation of biosynthetic process - GO:0009891; protein secretion - GO:0009306; enzyme linked receptor protein signaling pathway - GO:0007167; regulation of primary metabolic process - GO:0080090; nucleobase-containing compound metabolic process - GO:0006139; common-partner SMAD protein phosphorylation - GO:0007182; heterocycle biosynthetic process - GO:0018130; insulin secretion - GO:0030073; response to alcohol - GO:0097305; positive regulation of cell communication - GO:0010647; organ growth - GO:0035265; epithelium development - GO:0060429; regulation of developmental process - GO:0050793; macromolecule metabolic process - GO:0043170; positive regulation of transcription; DNA-templated - GO:0045893; regulation of stem cell differentiation - GO:2000736; negative regulation of macromolecule biosynthetic process - GO:0010558; negative regulation of cellular macromolecule biosynthetic process - GO:2000113; positive regulation of developmental process - GO:0051094; positive regulation of BMP signaling pathway - GO:0030513; response to lipid - GO:0033993; positive regulation of macromolecule metabolic process - GO:0010604; regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090092; negative regulation of nucleobase-containing compound metabolic process - GO:0045934; single-organism process - GO:0044699; axis specification - GO:0009798; zygotic specification of dorsal/ventral axis - GO:0007352; positive regulation of rna biosynthetic process - GO:1902680; activin receptor signaling pathway - GO:0032924; regulation of cell proliferation - GO:0042127; primary mirna processing - GO:0031053; negative regulation of rna metabolic process - GO:0051253;