| Cellular component | protein complex - GO:0043234; activin receptor complex - GO:0048179; cellular_component - GO:0005575; intracellular part - GO:0044424; occluding junction - GO:0070160; membrane part - GO:0044425; organelle - GO:0043226; catalytic complex - GO:1902494; transferase complex - GO:1990234; plasma membrane - GO:0005886; protein kinase complex - GO:1902911; membrane raft - GO:0045121; membrane - GO:0016020; serine/threonine protein kinase complex - GO:1902554; cell surface - GO:0009986; tight junction - GO:0005923; cytoplasmic part - GO:0044444; transforming growth factor beta receptor homodimeric complex - GO:0070022; nucleus - GO:0005634; plasma membrane part - GO:0044459; intracellular organelle - GO:0043229; bicellular tight junction - GO:0005923; endosome - GO:0005768; membrane-bounded organelle - GO:0043227; cell-cell junction - GO:0005911; macromolecular complex - GO:0032991; receptor complex - GO:0043235; cell part - GO:0044464; intracellular membrane-bounded organelle - GO:0043231; cell junction - GO:0030054; integral component of plasma membrane - GO:0005887; |
| Molecular function | transforming growth factor beta-activated receptor activity - GO:0005024; receptor activity - GO:0004872; binding - GO:0005488; atp binding - GO:0005524; purine ribonucleotide binding - GO:0032555; I-SMAD binding - GO:0070411; i-smad binding - GO:0070411; metal ion binding - GO:0046872; transferase activity; transferring phosphorus-containing groups - GO:0016772; nucleotide binding - GO:0000166; ribonucleoside binding - GO:0032549; small molecule binding - GO:0036094; receptor binding - GO:0005102; transmembrane receptor protein serine/threonine kinase activity - GO:0004675; protein binding - GO:0005515; adenyl nucleotide binding - GO:0030554; receptor signaling protein serine/threonine kinase activity - GO:0004702; heterocyclic compound binding - GO:1901363; receptor signaling protein activity - GO:0005057; nucleoside binding - GO:0001882; signal transducer activity - GO:0004871; anion binding - GO:0043168; carbohydrate derivative binding - GO:0097367; protein serine/threonine kinase activity - GO:0004674; type ii transforming growth factor beta receptor binding - GO:0005114; transforming growth factor beta receptor binding - GO:0005160; molecular transducer activity - GO:0060089; type II transforming growth factor beta receptor binding - GO:0005114; SMAD binding - GO:0046332; growth factor binding - GO:0019838; cytokine binding - GO:0019955; cytokine receptor binding - GO:0005126; cation binding - GO:0043169; transforming growth factor beta receptor activity; type i - GO:0005025; transferase activity - GO:0016740; protein kinase activity - GO:0004672; phosphotransferase activity; alcohol group as acceptor - GO:0016773; transmembrane receptor protein kinase activity - GO:0019199; transforming growth factor beta binding - GO:0050431; purine ribonucleoside binding - GO:0032550; molecular_function - GO:0003674; kinase activity - GO:0016301; ribonucleotide binding - GO:0032553; purine nucleoside binding - GO:0001883; smad binding - GO:0046332; ATP binding - GO:0005524; adenyl ribonucleotide binding - GO:0032559; purine nucleotide binding - GO:0017076; ion binding - GO:0043167; nucleoside phosphate binding - GO:1901265; activin binding - GO:0048185; catalytic activity - GO:0003824; purine ribonucleoside triphosphate binding - GO:0035639; transforming growth factor beta receptor activity; type I - GO:0005025; signaling receptor activity - GO:0038023; organic cyclic compound binding - GO:0097159; transmembrane signaling receptor activity - GO:0004888; |
| Biological process | cellular response to organic substance - GO:0071310; transforming growth factor beta receptor signaling pathway - GO:0007179; positive regulation of protein kinase b signaling - GO:0051897; protein complex subunit organization - GO:0071822; endothelial cell migration - GO:0043542; signal transduction by phosphorylation - GO:0023014; negative regulation of response to stimulus - GO:0048585; regulation of transforming growth factor beta receptor signaling pathway - GO:0017015; regulation of intracellular transport - GO:0032386; regulation of rna metabolic process - GO:0051252; regulation of protein import into nucleus - GO:0042306; angiogenesis - GO:0001525; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation - GO:1905007; single organism reproductive process - GO:0044702; locomotion - GO:0040011; transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0007178; response to transforming growth factor beta - GO:0071559; chordate embryonic development - GO:0043009; skeletal system morphogenesis - GO:0048705; positive regulation of phosphorylation - GO:0042327; regulation of signaling - GO:0023051; regulation of nucleic acid-templated transcription - GO:1903506; regulation of cell growth - GO:0001558; primary metabolic process - GO:0044238; epithelial cell migration - GO:0010631; cell motility - GO:0048870; positive regulation of endothelial cell proliferation - GO:0001938; cellular response to transforming growth factor beta stimulus - GO:0071560; epicardium morphogenesis - GO:1905223; male gonad development - GO:0008584; positive regulation of biological process - GO:0048518; movement of cell or subcellular component - GO:0006928; peptidyl-serine phosphorylation - GO:0018105; regulation of protein transport - GO:0051223; signal transduction - GO:0007165; regulation of protein phosphorylation - GO:0001932; in utero embryonic development - GO:0001701; regulation of cell communication - GO:0010646; regulation of protein localization - GO:0032880; positive regulation of transcription; dna-templated - GO:0045893; skeletal system development - GO:0001501; lens development in camera-type eye - GO:0002088; cellular metabolic process - GO:0044237; regulation of macromolecule biosynthetic process - GO:0010556; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090100; regulation of cellular process - GO:0050794; negative regulation of cell proliferation - GO:0008285; regulation of mapk cascade - GO:0043408; kidney development - GO:0001822; hematopoietic or lymphoid organ development - GO:0048534; positive regulation of signaling - GO:0023056; embryonic skeletal system morphogenesis - GO:0048704; regulation of transcription; DNA-templated - GO:0006355; ameboidal-type cell migration - GO:0001667; positive regulation of signal transduction - GO:0009967; regulation of macromolecule metabolic process - GO:0060255; pattern specification process - GO:0007389; macromolecule modification - GO:0043412; regulation of nucleocytoplasmic transport - GO:0046822; positive regulation of cellular process - GO:0048522; regulation of response to stimulus - GO:0048583; regulation of multicellular organismal development - GO:2000026; positive regulation of kinase activity - GO:0033674; cellular component organization or biogenesis - GO:0071840; positive regulation of gene expression - GO:0010628; embryonic morphogenesis - GO:0048598; coronary artery morphogenesis - GO:0060982; negative regulation of developmental process - GO:0051093; phosphorylation - GO:0016310; organ development - GO:0048513; regulation of cell death - GO:0010941; regulation of cell differentiation - GO:0045595; anterior/posterior pattern specification - GO:0009952; embryo development ending in birth or egg hatching - GO:0009792; organ morphogenesis - GO:0009887; metabolic process - GO:0008152; activation of protein kinase activity - GO:0032147; parathyroid gland development - GO:0060017; embryonic organ morphogenesis - GO:0048562; cell differentiation - GO:0030154; regulation of gene expression - GO:0010468; protein deubiquitination - GO:0016579; positive regulation of cell projection organization - GO:0031346; negative regulation of transforming growth factor beta receptor signaling pathway - GO:0030512; regulation of cellular protein localization - GO:1903827; artery morphogenesis - GO:0048844; positive regulation of cell growth - GO:0030307; protein metabolic process - GO:0019538; regulation of biological process - GO:0050789; cell migration - GO:0016477; cellular response to stimulus - GO:0051716; cell death - GO:0008219; regulation of chondrocyte differentiation - GO:0032330; response to oxygen-containing compound - GO:1901700; regulation of cell development - GO:0060284; positive regulation of transport - GO:0051050; negative regulation of signal transduction - GO:0009968; regulation of multicellular organismal process - GO:0051239; response to organic cyclic compound - GO:0014070; regulation of phosphate metabolic process - GO:0019220; anatomical structure morphogenesis - GO:0009653; positive regulation of epithelial to mesenchymal transition - GO:0010718; positive regulation of protein kinase B signaling - GO:0051897; cellular macromolecule metabolic process - GO:0044260; regulation of cellular component organization - GO:0051128; regulation of cellular protein metabolic process - GO:0032268; regulation of protein modification by small protein conjugation or removal - GO:1903320; extracellular matrix organization - GO:0030198; response to sterol - GO:0036314; regulation of cellular localization - GO:0060341; developmental process - GO:0032502; regulation of anatomical structure morphogenesis - GO:0022603; cell morphogenesis - GO:0000902; response to stimulus - GO:0050896; positive regulation of programmed cell death - GO:0043068; response to chemical - GO:0042221; blastocyst development - GO:0001824; positive regulation of molecular function - GO:0044093; cellular protein modification process - GO:0006464; positive regulation of cell proliferation - GO:0008284; negative regulation of cell differentiation - GO:0045596; regulation of smad protein import into nucleus - GO:0060390; cellular process - GO:0009987; negative regulation of cell communication - GO:0010648; positive regulation of rna metabolic process - GO:0051254; negative regulation of extrinsic apoptotic signaling pathway - GO:2001237; cell activation - GO:0001775; cell morphogenesis involved in differentiation - GO:0000904; regulation of programmed cell death - GO:0043067; embryonic cranial skeleton morphogenesis - GO:0048701; regulation of phosphorylation - GO:0042325; regulation of extrinsic apoptotic signaling pathway - GO:2001236; single-organism developmental process - GO:0044767; regionalization - GO:0003002; epithelial to mesenchymal transition - GO:0001837; organic substance metabolic process - GO:0071704; cell cycle arrest - GO:0007050; pathway-restricted SMAD protein phosphorylation - GO:0060389; positive regulation of mapk cascade - GO:0043410; regulation of establishment of protein localization - GO:0070201; positive regulation of transferase activity - GO:0051347; regulation of transcription; dna-templated - GO:0006355; reproductive process - GO:0022414; cardiac epithelial to mesenchymal transition - GO:0060317; regulation of rna biosynthetic process - GO:2001141; positive regulation of protein transport - GO:0051222; positive regulation of filopodium assembly - GO:0051491; positive regulation of intracellular signal transduction - GO:1902533; death - GO:0016265; positive regulation of cellular component organization - GO:0051130; positive regulation of protein import into nucleus - GO:0042307; regulation of protein localization to nucleus - GO:1900180; regulation of nucleobase-containing compound metabolic process - GO:0019219; regulation of cartilage development - GO:0061035; regulation of protein binding - GO:0043393; cellular component morphogenesis - GO:0032989; regulation of transport - GO:0051049; regulation of kinase activity - GO:0043549; positive regulation of cell migration - GO:0030335; regulation of cytoplasmic transport - GO:1903649; positive regulation of cell communication - GO:0010647; ventricular septum morphogenesis - GO:0060412; response to alcohol - GO:0097305; regulation of transferase activity - GO:0051338; regulation of protein metabolic process - GO:0051246; positive regulation of macromolecule metabolic process - GO:0010604; positive regulation of phosphorus metabolic process - GO:0010562; negative regulation of apoptotic process - GO:0043066; response to lipid - GO:0033993; positive regulation of protein modification process - GO:0031401; regulation of catalytic activity - GO:0050790; regulation of stem cell differentiation - GO:2000736; positive regulation of transcription; DNA-templated - GO:0045893; regulation of developmental process - GO:0050793; regulation of cell cycle - GO:0051726; macromolecule metabolic process - GO:0043170; regulation of filopodium assembly - GO:0051489; positive regulation of intracellular transport - GO:0032388; apoptotic process - GO:0006915; single-organism process - GO:0044699; mesenchymal cell differentiation - GO:0048762; regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090092; positive regulation of cell death - GO:0010942; pathway-restricted smad protein phosphorylation - GO:0060389; regulation of cell proliferation - GO:0042127; developmental process involved in reproduction - GO:0003006; positive regulation of catalytic activity - GO:0043085; activin receptor signaling pathway - GO:0032924; cellular process involved in reproduction in multicellular organism - GO:0022412; negative regulation of apoptotic signaling pathway - GO:2001234; positive regulation of rna biosynthetic process - GO:1902680; regulation of phosphorus metabolic process - GO:0051174; cellular response to endogenous stimulus - GO:0071495; protein phosphorylation - GO:0006468; anatomical structure development - GO:0048856; positive regulation of cellular component movement - GO:0051272; regulation of protein kinase b signaling - GO:0051896; activation of mapkk activity - GO:0000186; ventricular compact myocardium morphogenesis - GO:0003223; negative regulation of cellular response to growth factor stimulus - GO:0090288; multicellular organismal process - GO:0032501; regulation of growth - GO:0040008; regulation of protein ubiquitination - GO:0031396; negative regulation of cellular process - GO:0048523; gland development - GO:0048732; peptidyl-serine modification - GO:0018209; negative regulation of epithelial cell proliferation - GO:0050680; extracellular structure organization - GO:0043062; heart development - GO:0007507; positive regulation of nucleocytoplasmic transport - GO:0046824; peptidyl-threonine phosphorylation - GO:0018107; regulation of metabolic process - GO:0019222; positive regulation of intracellular protein transport - GO:0090316; regulation of cellular component biogenesis - GO:0044087; embryo development - GO:0009790; gonad development - GO:0008406; angiogenesis involved in coronary vascular morphogenesis - GO:0060978; regulation of cellular biosynthetic process - GO:0031326; regulation of cellular response to growth factor stimulus - GO:0090287; regulation of protein modification process - GO:0031399; regulation of cellular response to transforming growth factor beta stimulus - GO:1903844; collagen fibril organization - GO:0030199; positive regulation of protein kinase activity - GO:0045860; regulation of nitrogen compound metabolic process - GO:0051171; regulation of apoptotic signaling pathway - GO:2001233; wound healing - GO:0042060; intracellular signal transduction - GO:0035556; system development - GO:0048731; positive regulation of pathway-restricted smad protein phosphorylation - GO:0010862; positive regulation of cellular protein localization - GO:1903829; regulation of pathway-restricted smad protein phosphorylation - GO:0060393; regulation of primary metabolic process - GO:0080090; enzyme linked receptor protein signaling pathway - GO:0007167; negative regulation of programmed cell death - GO:0043069; positive regulation of biosynthetic process - GO:0009891; positive regulation of response to stimulus - GO:0048584; cell fate commitment - GO:0045165; post-embryonic development - GO:0009791; positive regulation of apoptotic process - GO:0043065; phosphorus metabolic process - GO:0006793; regulation of molecular function - GO:0065009; peptidyl-threonine modification - GO:0018210; stem cell differentiation - GO:0048863; cellular developmental process - GO:0048869; negative regulation of cellular response to transforming growth factor beta stimulus - GO:1903845; regulation of epithelial cell proliferation - GO:0050678; response to wounding - GO:0009611; positive regulation of apoptotic signaling pathway - GO:2001235; regulation of apoptotic process - GO:0042981; response to growth factor - GO:0070848; positive regulation of phosphate metabolic process - GO:0045937; regulation of intracellular protein transport - GO:0033157; cell cycle process - GO:0022402; regulation of endothelial cell proliferation - GO:0001936; palate development - GO:0060021; positive regulation of SMAD protein import into nucleus - GO:0060391; positive regulation of nucleobase-containing compound metabolic process - GO:0045935; positive regulation of stress fiber assembly - GO:0051496; germ cell migration - GO:0008354; activation of MAPKK activity - GO:0000186; peptidyl-amino acid modification - GO:0018193; response to stress - GO:0006950; regulation of cellular macromolecule biosynthetic process - GO:2000112; regulation of intracellular signal transduction - GO:1902531; ventricular trabecula myocardium morphogenesis - GO:0003222; positive regulation of smad protein import into nucleus - GO:0060391; biological regulation - GO:0065007; negative regulation of endothelial cell proliferation - GO:0001937; single-organism cellular process - GO:0044763; response to endogenous stimulus - GO:0009719; positive regulation of epithelial cell proliferation - GO:0050679; endothelial cell activation - GO:0042118; regulation of signal transduction - GO:0009966; regulation of epithelial to mesenchymal transition - GO:0010717; negative regulation of cell death - GO:0060548; pharyngeal system development - GO:0060037; positive regulation of occluding junction disassembly - GO:1905075; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway - GO:0090101; macromolecular complex subunit organization - GO:0043933; proepicardium development - GO:0003342; biological_process - GO:0008150; cellular response to growth factor stimulus - GO:0071363; regulation of cell morphogenesis - GO:0022604; positive regulation of pathway-restricted SMAD protein phosphorylation - GO:0010862; positive regulation of cellular biosynthetic process - GO:0031328; response to organic substance - GO:0010033; positive regulation of protein phosphorylation - GO:0001934; positive regulation of nitrogen compound metabolic process - GO:0051173; positive regulation of macromolecule biosynthetic process - GO:0010557; cellular response to chemical stimulus - GO:0070887; positive regulation of cellular metabolic process - GO:0031325; regulation of binding - GO:0051098; negative regulation of biological process - GO:0048519; cellular protein metabolic process - GO:0044267; positive regulation of protein metabolic process - GO:0051247; response to cholesterol - GO:0070723; positive regulation of cellular protein metabolic process - GO:0032270; regulation of cell projection organization - GO:0031344; anatomical structure formation involved in morphogenesis - GO:0048646; regulation of protein kinase activity - GO:0045859; positive regulation of protein localization to nucleus - GO:1900182; cellular component organization - GO:0016043; protein modification process - GO:0036211; positive regulation of cytoplasmic transport - GO:1903651; phosphate-containing compound metabolic process - GO:0006796; regulation of localization - GO:0032879; regulation of biosynthetic process - GO:0009889; cell surface receptor signaling pathway - GO:0007166; positive regulation of nucleic acid-templated transcription - GO:1903508; regulation of cell projection assembly - GO:0060491; programmed cell death - GO:0012501; positive regulation of cellular component biogenesis - GO:0044089; negative regulation of signaling - GO:0023057; negative regulation of chondrocyte differentiation - GO:0032331; regulation of cellular metabolic process - GO:0031323; negative regulation of cartilage development - GO:0061037; neuron fate commitment - GO:0048663; regulation of cell morphogenesis involved in differentiation - GO:0010769; negative regulation of multicellular organismal process - GO:0051241; positive regulation of metabolic process - GO:0009893; single-organism metabolic process - GO:0044710; reproductive structure development - GO:0048608; positive regulation of growth - GO:0045927; thymus development - GO:0048538; regulation of protein targeting - GO:1903533; negative regulation of cell cycle - GO:0045786; single-multicellular organism process - GO:0044707; regulation of cellular component movement - GO:0051270; regulation of cardiac muscle cell proliferation - GO:0060043; blood vessel morphogenesis - GO:0048514; |
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