| a major tumor suppressive role for miR-708, which may offer an attractive new target for prognostic and therapeutic intervention in renal cell carcinoma | kidney, |
| MiR-708 may play an important role as a tumor suppressor in GBM. | GBM, |
| miRNA-708 acts as a tumor suppressor because it negatively regulates the anti-apoptotic protein c-FLIPL and regulates the sensitivity of renal cancer cells to various apoptotic stimuli. | kidney, |
| Tumor-Suppressive MicroRNA-708 Targets Notch1 to Suppress Cell Proliferation and Invasion in Gastric Cancer | gastric, |
| miR-708 inhibited AKT/beta-catenin signaling, which is activated by SPHK2. In addition, miR-708 was transcriptionally repressed by EZH2 (enhancer of zeste homolog 2)-induced histone H3 lysine 27 trimethylation and promoter methylation. In summary, these findings revealed that miR-708 is a glioma tumor suppressor. | glioma, |
| miRNA-708 functions as a tumor suppressor in colorectal cancer by targeting ZEB1 through Akt/mTOR signaling pathway | colorectal, |
| Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers. | lung, |
| MiR-708 may act as an oncogene and induce the carcinogenicity of bladder cancer by down-regulating Caspase-2 level. | bladder, |
| miR-708 promotes the development of bladder carcinoma via direct repression of Caspase-2. | bladder, |
| miRNA-708 acts as an oncogene contributing to tumor growth and disease progression by directly downregulating TMEM88 | None |