Sentence and cancer type
Showing 1-3 of 3 items.
SentenceCancertype
Findings reveal that RanBPM plays a novel role in regulating Mgl-1 stability and contributes to its biological function as a tumor suppressor.None
RanBP9 physically interacts with the tumor suppressor p73 and increases endogenous p73alpha levels at both transcriptional and post-translational levels.None
Our work shows that RanBPM, together with the CTLH complex, associates with HDAC6 and restricts cell migration through inhibition of HDAC6 activity. This study uncovers a novel function for the CTLH complex and suggests that it could have a tumour suppressive role in restricting HDAC6 oncogenic properties.None