Sentence and cancer type
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SentenceCancertype
A 2.62 Mbp minimal region of genomic loss of chromosome 16q22 was found in retinoblastoma which contains a hotspot CDH11, implicating CDH11as a potential tumor suppressor gene in retinoblastoma.retinoblastoma,
Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell deathretinoblastoma,
Data indicate that CDH11 as a functional tumor suppressor and an important antagonist of Wnt/beta-catenin signaling, with frequent epigenetic inactivation in common carcinomas.None
primary aneurysmal bone cysts are mesenchymal neoplasms exhibiting USP6 and/or CDH11 oncogenic rearrangementsneoplasm,
suppression of MUC1 by miR-145 causes a reduction of beta-catenin as well as the oncogenic cadherin 11None