| topors functions as a negative regulator of cell growth, and possibly as a tumor suppressor | None |
| topors mediates p53-dependent cellular responses induced by DNA damage, suggesting its physiological role as a tumor suppressor | None |
| The findings suggest that TOPORS may function as a tumor suppressor by regulating mSin3A and other proteins involved in chromatin modification. | None |
| TOPORS, a tumor suppressor protein, contributes to the maintenance of higher-order chromatin architecture | None |