Sentence and cancer type
Showing 1-7 of 7 items.
SentenceCancertype
our findings uncover a tumour suppressor function for CDK8 in vivo and suggest that the role of CDK8 activity in driving oncogenesis is context-specific.None
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. colorectal,
Revving the Throttle on an oncogene: CDK8 takes the driver seat. None
The authors show, using a human tumor cell line, that CDK8 is a positive regulator of genes within the serum response network, including several members of the activator protein 1 and early growth response family of oncogenic transcription factors.None
CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency. None
we identify a role for the CDK8 oncogene in regulating tumor differentiation and stem cell pluripotencyNone
our findings uncover a tumour suppressor function for CDK8 in vivo and suggest that the role of CDK8 activity in driving oncogenesis is context-specific.None