Showing 21-29 of 29 items.

Sentence	Cancertype
p27 is a key target of MDM4 oncogenic activity in breast cancer (BC) with mutant p53.	breast,
Cytoplasmic p27 is a novel prognostic biomarker and oncogenic protein for nasopharyngeal carcinoma.	nasopharyngeal,laryngeal,
independently of its role as a CDK inhibitor, p27Kip1 promoted stem cell expansion and functioned as a dominant oncogene in vivo	None
[p27Kip1: tumor suppressor and oncogene?].	None
novel aspects of the p27(KIP1) protein, which displays genetically separable tumor suppressing and oncogenic functions.	None
propose that the p27(CK-) protein needs to be localized in the cytoplasm in order to function as an oncogene, otherwise it just behaves similar to a null allele	None
Novel oncogenic function of p27Kip1: retention and destabilization of the pro-apoptotic PTEN outside of the nucleus.	None
These findings support an important role of p27 in Notch1-dependent oncogenic signaling.	None
loss of CDKN1B increased the prevalence of cell cycle regulator defects in immature T-ALL, usually only ascribed to CDKN2A/B deletions, and that CDKN1B deletions frequently coincide with expression of MEF2C, considered as one of the driving oncogenes in immature early T-cell precursor (ETP) ALL	None