| Results demonstrated that linc-p21 expression level was downregulated in gastric cancer (GC) cells and tissues and its overexpression suppressed the GC cell growth, cell cycle, and migration as well as the radiosensitivity by regulating the beta-catenin signaling pathway. These data suggested that lincRNA-p21 acted as a tumor suppressor gene in the development of GC. | gastric, |
| Here, we report the identification of lincRNAs that are regulated by p53. One of these lincRNAs (lincRNA-p21) serves as a repressor in p53-dependent transcriptional responses. | None |
| In this review, author summarized the gene as tumor suppressor in table 2. | None |