Sentence and cancer type
Showing 181-200 of 215 items.
SentenceCancertype
Loss of tumor suppressors RUNX3 and CDKN2A were related to recurrence-risk and warrants further investigationNone
Human DMTF1? antagonizes DMTF1? regulation of the p14(ARF) tumor suppressor and promotes cellular proliferationNone
degradation of MAGE-A11 promoted by the human p14-ARF tumor suppressor contributes to low levels of MAGE-A11 in nontransformed cellsNone
Data show that tumor suppressor p16(INK4A) inhibits interleukin-6 (IL-6) expression in a microRNA miR-146b-5p-dependent manner.None
Arf tumor suppressor as a new transcriptional target of nuclear EGFR and highlight Vps34 as an important regulator of the nuclear EGFR/Arf survival pathway.None
importance of p19(Arf) for the cellular response to the low-level DNA damage incurred in culture or upon oncogene expression, providing new insight into how p19(Arf) serves as a tumor suppressor.None
[DDX5 is a novel targeting protein of tumor suppressor ARF]None
K259-SUMOylation of DGCR8 promoted by p14ARF exerts a tumor-suppressive functionNone
Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarizationNone
Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytesNone
Increased the expression of tumor suppressor genes such as Cdkn2A, Rb1 and p53.None
The expression of three tumor suppressor genes encoded in the INK4/ARF locus (p15(INK4b), p16(INK4a), and p19(ARF)) was decreased in E6AP(-/-) embryo fibroblasts.None
Data show that the Wnt-effector hepatocyte nuclear factor 1-alpha (Tcf1) is recruited to and triggers transcription of the Ink4/Arf tumor suppressor locus, such as as p15Ink4b, p16Ink4a and p19Arf.None
IRES-Mediated Protein Translation Overcomes Suppression by the p14ARF Tumor Suppressor ProteinNone
Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient miceNone
Important role of the circadian clock as an Ink4a/Arf-dependent modulator of oncogene-induced cell fate decisions, reinforcing its function as a tumour-suppressor and the close interplay between the clock and the cell cycle network.None
Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arfNone
ARF is a tumor suppressor protein that has a pivotal role in the prevention of cancer development through regulating cell proliferation, senescence, and apoptosis. As a factor that induces senescence, the role of ARF as a tumor suppressor is closely linked to the p53-MDM2 axis, which is a key process that restrains tumor formation. Review.None
RXRalpha provokes tumor suppression through p53/p21/p16 and PI3K-AKT signaling pathways during stem cell differentiation and in cancer cells.None
Tumor Suppressor p14ARF Enhances IFN-?-Activated Immune Response by Inhibiting PIAS1 via SUMOylationNone