| Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells. | pancreatic, |
| combined with screening of K-ras mutations and allelic losses of tumor suppressors p16 and DPC4 represents a very sensitive approach in screening for pancreatic malignancy. | pancreatic, |
| P16INK4A is overexpressed in HR-HPV-infected cervical cancer, but its tumor suppressor action might be inhibited. | cervical, |
| ARF tumor suppressor has a role in mouse models of acute leukemias [review] | leukemia, |
| the tumor suppressor activity of ARF in melanoma-genesis is p53 independent [news] | skin, |
| Loss of heterozygosity (LOH) of the hDMP1 gene was detectable in approximately 35% of human lung carcinomas, which was found in mutually exclusive fashion with LOH of INK4a/ARF or that of P53. DMP1 is a pivotal tumor suppressor for human lung cancers. | lung, |
| A novel role for the Arf tumor suppressor protein in regulating phenotypes associated with tumor progression and metastasis in hepatocellular carcinoma cells. | liver, |
| Results indicate that TBX3 represses expression of p14(ARF) tumor suppressor in breast cancer. | breast, |
| These findings uncover a feedback regulatory circuit in the astrocytic lineage and demonstrate tumor suppressor role for p18(INK4C) in human glioblastoma wherein it functions cooperatively with other INK4 family. | glioblastoma, |
| Genistein induces the expression of tumor suppressor genes p21 (WAF1/CIP1/KIP1) and p16 (INK4a) with a concomitant decrease in cyclins in prostate cancer cells. | prostate, |
| Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines. | glioma, |
| Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer. | endometrial, |
| evaluated the expression of the tumour suppressors p14, p16 and p53 in pre-malignant and malignant squamous skin tumours, and its relation with risk factors for skin carcinogenesis (HPV, immune status and sun exposure) | skin, |
| Data demonstrate that Bmi1 promotes prostate tumorigenesis, and that Bmi1 expression is associated with a reduction in tumor suppressors p16(INK4A) and p14(ARF). | prostate, |
| Methylation status of p16 INK4A tumor suppressor gene in Iranian patients with sporadic breast cancer. | breast, |
| Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. | glioma, |
| Oncogene-induced senescence does not require the p16(INK4a) or p14ARF melanoma tumor suppressors. | skin, |
| p16 might act as a tumor suppressor in colorectal carcinomas and was more frequently methylated in advanced colorectal carcinomas. | colorectal, |
| CDK inhibitor p16 tumor suppressors were genes activated in early endometrial endometrioid carcinoma (stages I-II). | endometrial, |
| p16 might act as a tumor suppressor in gastric carcinomas and appears to be more frequently methylated in lymphatic-invasive gastric carcinomas. | gastric, |