Sentence and cancer type
Showing 141-160 of 215 items.
SentenceCancertype
Role of the tumor suppressor ARF in oncogenesisNone
The results unveil a backup tumor suppressor role for p16(Ink4a) in the event of p53 inactivation, expanding our understanding of how p16(Ink4a) expression is regulated in vivo.None
DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance.None
Studies indicate that p53, arf and other tumor suppressors might be barriers to reprogramming somatic cells for the generation of induced pluripotent stem cells.None
A quantitative model for age-dependent expression of the p16INK4a tumor suppressor.None
Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria.None
The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis.None
Results define a mechanism by which the ARF tumor suppressor targets the translational repression of specific oncogenes during neoplastic transformation.None
The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I.None
Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.None
Aberrant epigenetic silencing of tumor suppressor genes is reversed by direct reprogramming.None
Ablation of either USP7 or USP11 in primary human fibroblasts results in de-repression of the INK4a tumour suppressor accompanied by loss of Polycomb repressive complex 1 binding at the locus and a senescence-like proliferative arrest.None
The p16(INK4A) tumor suppressor regulates cellular oxidative stress.None
p16 controls the cell cycle as tumor suppressorNone
Alterations in the tumor suppressor gene p16(INK4A) are associated with aggressive behavior of penile carcinomas.None
p16(Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors.None
Data show that VentX is a direct transcriptional activator of p53-p21 and p16ink4a-Rb tumor suppression pathways.None
Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.None
Cancerous tissues from 30 patients with HPSCC were examined for LOH in 4 tumor suppressor genes (TSGs) (p16, Rb, E-cadherin, and p53) at loci 9p21, 13q21, 6q22, and 17p13, respectively, using microsatellite markers amplified by polymerase chain reaction.None
Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.None