| Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function. | None |
| Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells. | None |
| Alterations of tumor suppressor genes such as CDKN2A and oncogenes such as ERBB2 play a role in the progression of intestinal metaplasia to adenocarcinoma in patients with Barrett_s esophagus. | None |
| Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. | None |
| The tumor suppressor p33ING1b upregulates p16INK4a expression and induces cellular senescence. | None |
| Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint. | None |
| The tumor suppressor ARF regulates innate immune responses in mice. | None |
| [review] Major tumor suppressor ARF in the nucleus participates in crosstalk between host cells and mitochondria by activating p53 target genes involved in varied mitochondrial functions. | None |
| Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus. | None |
| Tumor suppressor activity of p14ARF is regulated by its phosphorylation. | None |
| Up-regulation of survivin during immortalization of human myofibroblasts is linked to repression of tumor suppressor p16(INK4a) protein and confers resistance to oxidative stress. | None |
| Arf tumor suppressor and miR-205 regulate cell adhesion and formation of extraembryonic endoderm from pluripotent stem cells. | None |
| Precise regulation of p16(INK4a) is essential to tissue homeostasis, maintaining a coordinated balance between tumor suppression and aging. | None |
| HKR3 potently activated the transcription of the tumor suppressor gene ARF by acting on the proximal promoter region (bp, -149 approximately +53), which contains Sp1 and FBI-1 binding elements (FREs). | None |
| Data indicate that Arf tumor suppressor blocks the functional interaction between c-Myc and p68 DEAD-box protein (DDX5). | None |
| The ARF tumor suppressor is a key sensor of signals that instruct a cell to grow and proliferate and is appropriately localized in nucleoli to limit these processes | None |
| Data suggest that EZH2 depletion promotes the progression of senescence by mediating the activation of tumor suppressor genes p21 and p16. | None |
| Epigenomic activity of Ind was evident as de-methylation of the tumor suppressor p16(INK4a) gene promoter, reactivation of the silenced mRNA expression and accumulation of p16(INK4a), a major controller of cell cycle. | None |
| the tumor suppressor p14(ARF) may have an important role in counteracting proliferation of aneuploid cells by activating p53-dependent apoptosis | None |
| Jnk2 promoted ubiquitination and proteasomal degradation of the small mitochondrial form of the tumor suppressor ARF. | None |