| p18INK4c may function as a tumor suppressor in Hodgkin lymphoma, and inactivation may contribute to cell cycle deregulation and defective terminal differentiation of the Reed-Sternberg cells. | lymphoma, |
| Mutational analysis of p27 (CDKN1B) and p18 (CDKN2C) in sporadic pancreatic endocrine tumors argues against tumor-suppressor function. | pancreatic, |
| Studies identify p18(INK4c) as a glioblastoma multiforme tumor suppressor gene, revealing an additional mechanism leading to aberrant activation of cyclin/cdk complexes in this terrible malignancy. | glioblastoma, |
| These findings uncover a feedback regulatory circuit in the astrocytic lineage and demonstrate tumor suppressor role for p18(INK4C) in human glioblastoma wherein it functions cooperatively with other INK4 family. | glioblastoma, |
| P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma | PCPG,thyroid, |
| Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A. | None |
| Here we show that treatment of p18 null and heterozygous mice with a chemical carcinogen resulted in tumor development at an accelerated rate.Hence, p18 is a haploinsufficient tumor suppressor in mice. | None |
| The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma. | None |
| p18Ink4c and Pten cooperate in tumor suppression by constraining a positive regulatory loop between cell growth and cell cycle control pathways. | None |
| Cdk4 inhibitor p18(Ink4c) is a tumor suppressor in cyclin D1-driven PNET. | None |
| Host Tumor Suppressor p18(INK4c) Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis | None |
| Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. | None |