| Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc. | thyroid, |
| results suggest that the oncogenic effect of the t(3;9) translocation may be due to the TFG-TEC chimeric protein and that fusion of the TFG (NTD) to the TEC protein produces a gain-of-function chimeric product | None |
| A TFG-TEC nuclear localization mutant forms complexes with the wild-type TFG-TEC oncoprotein and suppresses its activity. | None |
| The TFG-TEC oncoprotein induces transcriptional activation of the human beta-enolase gene via chromatin modification of the promoter region. | None |
| The DNA rearrangement that generates the TRK-T3 oncogene involves a novel gene on chromosome 3 whose product has a potential coiled-coil domain. | None |