Sentence and cancer type
Showing 41-47 of 47 items.
SentenceCancertype
DLC1 might act as a congenital heart disease-associated gene in addition to its role as a tumor suppressor in cancer.None
Subsequent studies have demonstrated that DLC-1 is generally expressed in normal human tissues as well as in rats, while it always exists inactivated or even lost in many human cancers, which characterizes DLC-1 as a potential tumor suppressor. [review]None
DLC1: a tumor suppressor that regulates Rho signalingNone
The tumor suppressor protein DLC1 maintains protein kinase D activity and Golgi secretory functionNone
these findings indicate cooperation between the SRC, ERK1/2, and AKT kinases to reduce DLC1 Rho-GAP and tumor suppressor activities in cancer cells, which can be reactivated by the kinase inhibitors.None
A tumor suppressor DLC1: The functions and signal pathwaysNone
Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased FunctionNone
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