| Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in renal cancer cells. | kidney, |
| NDRG1 completely inhibits growth in anchorage-independent assays and in vivo supports a biological function as a tumor suppressor in pancreatic cancer. | pancreatic, |
| The results suggest that miR-182 plays an important role in the proliferation of human prostate cancer cells by directly suppressing the tumor supressor gene NDRG1. | prostate, |
| NDRG1 acts as a tumor suppressor in ovarian carcinogenesis and may be a potential therapeutic target in this disease. | ovarian, |
| Down-regulation of NDRG1 in gastric cancer metastatic progression was correlated to E-cadherin and MMP-9. NDRG1 acts as a tumor suppressor gene. | gastric, |
| Sequence analysis predicted a pseudotrypsin protease cleavage site between Cys49-Gly50. Such cleavage of NDRG1 in cancer cells may result in loss of NDRG1 tumour suppressive activity. | None |
| These findings suggest that nuclear NDRG1 has tumor suppressive effects, and the NDRG1 expression may have clinical values in ccRCC. | None |