| Cdx2 is a tumour suppressor gene involved in cancer progression in the distal colon. This action in adults is functionally and geographically distinct from its homeotic role during gut development. | colorectal, |
| EphA2 activation by ephrin-A1 induces tumor suppressor gene cdx-2 expression which attenuates cell proliferation, tumor growth and thus may be a promising therapeutic target against NSCLC. | lung, |
| CDX2 is frequently methylated in lung cancer, and expression of CDX2 is regulated by promoter region hypermethylation. CDX2 may serve as a tumor suppressor in lung cancer and inhibits lung cancer cell proliferation by suppressing Wnt signaling. | lung, |
| CDX2 is a tumor suppressor in colorectal cancer | colorectal, |
| this study shows that Aloe vera gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer | colorectal, |
| The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton | colorectal, |
| the downregulation of HNF4alpha is an important determinant of the reduced expression of the Cdx2 tumor suppressor gene in intestinal cancers. | None |
| Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing | None |
| The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia. | leukemia, |
| CDX2 is an amplified lineage-survival oncogene in colorectal cancer. | colorectal, |
| the proto-oncogene CDX2 is aberrantly expressed in the majority of cases with B-lineage ALL and T-ALL | None |