| These results demonstrate that promoter methylation is involved in the decreased expression of TIP30 tumor suppressor gene in human colorectal carcinoma. | colorectal, |
| TIP30 functions as a tumor suppressor to inhibit EGFR cytoplasmic and nuclear signaling and suppress adenocarcinogenesis in the lung. | lung, |
| These results suggest that TIP30, as a tumor suppressor in the bladder cancer, might be served as a target in cancer therapies in the future. | bladder, |
| Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor. | None |
| TIP30: A Novel Tumor-Suppressor Gene | None |
| Here, we identified the tumor suppressor protein TIP30 as novel inhibitor of cardiac hypertrophy and dysfunction. The results are relevant for human disease, since the authors found diminished cardiac TIP30 levels in samples from patients suffering from end-stage heart failure or hypertrophic cardiomyopathy. | None |