Sentence and cancer type
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Cancertype
Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene.
brain,glioma,
TRIM3 acts as a tumor suppressor in GBM by restoring asymmetric cell division.
GBM,
TRIM3 functions as a tumour suppressor in CRC progression. This tumour-suppressive function is exerted partially through regulation of p53 protein.
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