| Our findings indicate that TXNIP functions as a tumor suppressor in thyroid cells, and its downregulation is likely important in the transition from differentiated to advanced thyroid cancer | thyroid, |
| Data show that thioredoxin interacting protein (TXNIP) is a tumor suppressor that is downregulated in esophageal adenocarcinoma (EAC). | esophageal, |
| CircRNA RAPGEF5 (cRAPGEF5) significantly downregulated in renal cell carcinoma (RCC) tissues and correlated positively with aggressive clinical characteristics and independently predicted poor overall survival and recurrence-free survival. cRAPGEF5 functions as a sponge of oncogenic miR-27a-3p, which facilitates RCC proliferation and migration by targeting the suppressor gene TXNIP. | kidney, |
| Thioredoxin interacting protein (TXNIP) acts as a tumor suppressor in human prostate cancer | prostate, |
| Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. | None |
| In this study, we identify a known tumor suppressor gene, thioredoxin-interacting protein (Txnip) gene as a novel target of hnRNP G | None |
| The transformation associates the loss of thioredoxin-binding protein-2 (TBP-2), a tumor suppressor and regulator of lipid metabolism. | None |
| TXNIP (also named as VDUP-1 or TBP-2) was originally isolated in HL60 cells treated with Vitamin D3. Subsequently, it has been identified as a major redox regulator and a Tumor Suppressor Gene (TSG) in various solid tumors and hematological malignancies. | None |
| TXNIP functions as a tumor suppressor gene with loss of its expression associated with ductal carcinoma in situ recurrence | None |
| Research Progress of TXNIP as a Tumor Suppressor Gene Participating in the Metabolic Reprogramming and Oxidative Stress of Cancer Cells in Various Cancers | None |