| The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. | skin, |
| study demonstrate that expression of the MDA-7 tumor suppressor can negatively regulate iNOS expression in malignant melanoma cell lines | skin, |
| MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic mouse models of breast cancer | breast, |
| IL-24 inhibits AKT via regulating the HMGA1/miR-222 signaling node in human lung cancer cells and acts as an effective tumor suppressor. | lung, |
| Role of interleukin-24 in the tumor-suppressive effects of interferon-? on melanoma | skin, |
| Tumor suppressor MDA-7/IL-24 selectively inhibits vascular smooth muscle cell growth and migration. | None |
| MDA-7/IL-24, a novel tumor suppressor/cytokine is ubiquitinated and regulated by the ubiquitin-proteasome system, and inhibition of MDA-7/IL-24 degradation enhances the antitumor activity. | None |
| Grp170 enhances therapeutic activity of a novel tumor suppressor, mda-7/IL-24 | None |