| all of these features of CREB in HL strongly support its role as a tumor suppressor gene that can decelerate cell proliferation by inhibiting the expression of several cell cycle-related genes. | None |
| The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. | leukemia, |
| Loss of AP-2alpha expression in metastatic melanoma occurs via a dual mechanism involving binding of CREB to the AP-2alpha promoter and CREB-induced overexpression of another oncogenic transcription factor, E2F-1. | skin, |
| Our results demonstrate that CREB is proto-oncogene, and the phosphorylated level of CREB at Ser 133 site influences the growth and metastatic activity of renal cancer | kidney, |
| Decrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer. | kidney, |
| Results propose that CREB1 is an oncogene in renal cell carcinoma (RCC) and that upregulation of CREB1 by loss of tumor suppressive miR10b5p and miR3633p plays an important role in the tumorigenesis of RCC. | kidney, |
| The study adds evidence that CREB, a tumor oncogene, promotes renal cell carcinoma proliferation. It probably achieves this by increasing SKA2 expression | kidney, |
| CREB has a role in oncogenesis [review] | None |