| The identification of CBP inactivating mutations in conjunction with disruption of the second CBP allele strongly suggests that CBP is a tumour suppressor gene that contributes to ovarian tumorigenesis in humans. | ovarian, |
| show how CBP and PTEN interact to mediate tumor suppression in the prostate, establishing a central role for histone modification in the etiology of prostate cancer | prostate, |
| The CREBBP acetyltransferase is a haploinsufficient tumor suppressor in B-cell lymphoma. | lymphoma, |
| CBP/p300 acts as a tumour suppressor in epidermal keratinocytes by counteracting EGFR-Ras-Erk signaling, to prevent skin neoplasms. | skin,neoplasm, |
| CBP is a multifunctional transcriptional cofactor with tumor suppressor activity. Its CH3 domain binds to Sam68 in part through a conserved amino acid motif. | None |
| CREBBP and p300 may contribute to genome stability by fine-tuning the functions of DNA damage signaling and DNA repair factors, thereby expanding their role as tumor suppressors. (Review) | None |