| Tumor suppressor WTX gene mutation is rare in acute leukemias. | leukemia, |
| findings show that WTX, a protein encoded by a gene mutated in Wilms tumors, forms a complex with beta-catenin, AXIN1, beta-TrCP2 and APC; data provide a possible mechanistic explanation for the tumor suppressor activity of WTX | None |
| Gene has a tumor suppressor function in Wilms tumors, and is involved in beta-catenin destruction. | None |
| The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity. | None |
| Functional characterization of Wilms tumor-suppressor WTX and tumor-associated mutants. | None |
| The constellation of anomalies in Wtx null mice suggests that this tumor suppressor broadly regulates mesenchymal progenitor cells in multiple tissues. | None |
| A knock-in mouse line conditionally expressing the tumor suppressor WTX/AMER1 | None |