| Cten is a novel nuclear partner of beta-catenin, and has an oncogenic activity in colon cancers. | colorectal, |
| miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1. | breast, |
| A re-evaluation of the oncogenic nature of Wnt/beta-catenin signaling in melanoma and other cancers. | skin, |
| The human DEK oncogene stimulates beta-catenin signaling, invasion and mammosphere formation in breast cancer. | breast, |
| Thermostable direct hemolysin downregulates human colon carcinoma cell proliferation with the involvement of E-cadherin, and beta-catenin/Tcf-4 signaling. | colorectal, |
| lysyl oxidase proenzyme is shown to negatively regulate pro-oncogenic beta-catenin signaling in lung cancer cells. | lung, |
| Enhancement of canonical Wnt/beta-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. | liver, |
| MiR-155 is a liposarcoma oncogene that targets casein kinase-1alpha and enhances beta-catenin signaling. | sarcoma, |
| SOX10 is a novel oncogene in hepatocellular carcinoma through Wnt/beta-catenin/TCF4 cascade. | liver, |
| Beta-Catenin plays a major oncogenic role in oral squamous cell carcinoma, principally through increase in invasiveness due to loss of its membranous expression | oral |
| beta-catenin was predominantly associated with Na+/H+ exchanger regulating factor 1 (NHERF1) in a dynamic context and an increase of its oncogenic function through RAS-association domain family 1, isoform A (RASSF1A) inactivation in liver metastases. | liver, |
| Data illustrates a cooperative effect of the direct oncogenic signaling of mutant beta-catenin and MET in hepatocytes with hepatic tumor-promoting stroma induced by beta-catenin deficiency | liver, |
| multiomics analysis of a defined colorectal cancer cell model provides a significantly more comprehensive identification of functional molecular networks associated with oncogenic beta-catenin signaling. | colorectal, |
| Mutations in the oncogene, CTNNB1, predominantly cause Wnt activations that are nearly exclusive restrictions of Lynch syndrome-related high microsatellite instability (MSI-H) in Colorectal Cancer. | colorectal, |
| Sporadic medulloblastomas contain oncogenic beta-catenin mutations. | medulloblastomas, |
| Nuclear overexpression of the oncoprotein beta-catenin in colorectal cancer is localized predominantly at the invasion front. | colorectal, |
| The oncogenic activation of beta-catenin. | None |
| Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms tumors. | None |
| gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. | None |
| Hepatomegaly in transgenic mice expressing an oncogenic form of beta-catenin. | None |