Sentence and cancer type
Showing 61-71 of 71 items.
SentenceCancertype
alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. None
The potential for targeting oncogenic WNT/beta-catenin signaling in therapy. None
EB1 acts as an oncogene via activating beta-catenin/TCF pathway to promote cellular growth and inhibit apoptosis. None
Overexpression of the novel oncogene SALL4 and activation of the Wnt/beta-catenin pathway in myelodysplastic syndromes. None
The EWS/FLI1 oncogenic protein inhibits expression of the Wnt inhibitor DICKKOPF-1 gene and antagonizes beta-catenin/TCF-mediated transcription. None
Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers. None
Oncogenic mutations of CTNNB1 were found in hepatoblastoma. Wnt/beta-catenin target genes were significantly activated in the tumors without mutations. The clinical course in patients without CTNNB1 mutations seemed to be unfavorable.None
siRNA-mediated downregulation of beta-catenin could be valuable for defining gene expression and functional programs downstream of oncogenic beta-catenin signals.None
H. pylori induced activation of NF-kappaB and AP-1, cell proliferation, and expression of oncogenes (beta-catenein, c-myc) in AGS cells, which was inhibited by transfection of MAD3 and TAM67.None
Oncogenic beta-catenin and PI3K activities interact in the acquisition of multiple cancer-related phenotypes in organoids grown in Matrigel.None
Beta-catenin as oncogene: the smoking gun. None