Sentence and cancer type
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SentenceCancertype
results demonstrate that DDB2 is well conserved between humans and mice and functions as a tumor suppressor, at least in part, by controlling p53-mediated apoptosis after UV-irradiationNone
Ddb2 heterozygosity can facilitate tumor development as a haploinsufficient tumor suppressorNone
Damaged DNA binding protein 2 plays a role in breast cancer cell growth. breast,
These findings demonstrate for the first time that DDB2 can play a role as oncogene and may become a promising candidate as a predictive marker in breast cancer.breast,