| Using an in vivo mouse model of B16 melanoma, study demonstrated that GSDME may possess a bona fide tumor suppressor activity as GSDME-deficient melanoma cells form and grow larger tumors than their wild-type counterparts. | skin, |
| DFNA5 is a novel tumor suppressor gene in CRC and a valuable molecular marker for human cancer | None |
| tumor GSDME acts as a tumor suppressor by activating pyroptosis, enhancing anti-tumor immunity | None |