| These findings suggest that ASXL1 may function as a tumor suppressor in malignancies of the myeloid lineage by affecting stem or progenitor cell self-renewal or differentiation. | None |
| Asxl1 functions as a tumor suppressor to maintain hematopoietic cell homeostasis | None |
| Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals | None |
| Demonstration of ASXL1 mutation, a putative tumor suppressor gene, represents an important molecular abnormality in CML. Authors also showed that concomitant detection of BCR-ABL and JAK2V617F mutations has a relatively high incidence in Iranian patients. | None |