| identify Ment (Gm128) as an enhancer of lymphomagenesis that contributes to the tumor suppressor function of Dnmt3b | lymphoma, |
| data suggest that overexpression of DNMT1, DNMT3a, and DNMT3b might represent a critical event responsible for the epigenetic inactivation of multiple tumor suppressor genes, leading to the development of aggressive forms of sporadic breast cancer | breast, |
| Dnmt3b can act as a haploinsufficient tumor suppressor gene. | None |
| provide evidence that Dnmt3a and Dnmt3b function as tumor suppressor genes in the prevention of lymphoid malignancies in mice. | None |
| Dnmt3b plays a tumor suppressive role in MLL-AF9 AML progression | None |