Sentence and cancer type
Showing 201-220 of 279 items.
SentenceCancertype
Oncogenic KRAS impairs EGFR antibodies efficiency by C/EBPbeta-dependent suppression of EGFR expression. None
Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1. None
Temporal resolution of autophosphorylation for normal and oncogenic forms of EGFR and differential effects of gefitinib. None
Activation of beta-catenin by oncogenic PIK3CA and EGFR promotes resistance to glucose deprivation by inducing a strong antioxidant response. None
Our data highlights a new functional synergism between oncogenic EGFR and PIK3CA with WNT/beta-catenin conferring high tolerance to oxidative stress generated by nutrient deprivation.None
Hyperactivation of constitutively dimerized oncogenic EGF receptors by autocrine loops. None
Oncogenic RAS simultaneously protects against anti-EGFR antibody-dependent cellular cytotoxicity and EGFR signaling blockade. None
Oncogenic cooperation between SOCS family proteins and EGFR identified using a Drosophila epithelial transformation model. None
ERBB oncogene proteins as targets for monoclonal antibodies. None
Tissue samples burdened with specific oncogen signatures like EGFR gene amplification could be detected in precancerous lesion. This might improve follow-up and treatment protocols of glottic lesionsNone
EGFR, which is the product of a well-characterized oncogene in human cancers, suppresses the maturation of specific tumour-suppressor-like miRNAs in response to hypoxic stress through phosphorylation of argonaute 2 (AGO2) at Tyr 393None
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. None
A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth. None
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B. None
Specific inhibition of tumor cells by oncogenic EGFR specific silencing by RNA interference. None
Our findings highlight the importance of the polybasic juxtamembrane sequence in regulating the oncogenic potential of EGFR signaling.None
A comparative survey of functional footprints of EGFR pathway mutations in human cancers. None
Global functional profiles show that tumors driven by the EGFR oncogene often display an inflammatory response signature depending on the tissue type.None
Characterization of the epidermal growth factor receptor and the erbB oncogene product by site-specific antibodies. None
Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-kappaB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells. None