| A functional link between AHR and Wilms_ tumor suppressor gene in the regulation of renal morphogenesis | kidney, |
| Study provides evidence supporting the importance of AHR in tumor progression and host survival through the upregulation of ISX expression and promotion of tumor cell growth while restraining the expression of tumor suppressors in hepatocellular carcinoma (HCC), and thereby suggests a plausible mechanistic link between AHR and HCC. | liver, |
| These data support a mechanistic pathway for the putative tumour suppressive role of AHR specifically in pituitary adenomas, possibly through its role as a cell cycle co-regulator, even in the absence of exogenous ligands. | pituitary, |
| Aryl hydrocarbon receptor acts as a tumor suppressor in a syngeneic MC38 colon carcinoma tumor model | colorectal, |
| AhR is a tumor suppressor-like gene in blioblastoma (GBM); future studies are required to investigate whether the AhR could be a potential drug target for treating patients with GBM who express this receptor | GBM,glioblastoma, |
| in its basal state in the absence of a xenobiotic ligand, the Ahr gene functions as a tumor suppressor gene, and that its silencing may be associated with cancer progression. | None |
| Activation of the aryl hydrocarbon receptor increases Ube213 gene expression, resulting in increased tumor suppressor protein p53 ubiquitination and degradation. | None |
| AhR plays dual tumor suppressor roles; it acts as a regulator of both beta-catenin degradation and anti-inflammation in the intestine. | None |
| AHR may function as a tumor suppressor. | None |