Sentence and cancer type
Showing 101-120 of 198 items.
SentenceCancertype
The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway. None
The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. None
Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. None
Akt phosphorylates Tal1 oncoprotein and inhibits its repressor activity. None
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson s disease. None
FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway. None
Proto-oncogene TCL1: more than just a coactivator for Akt. None
KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway. None
Ang1 protects cardiomyocytes from oxidative stress-induced apoptosis by regulating the activity of Proto-Oncogene Proteins c-aktNone
a subpopulation of Akt is cholesterol sensitive and the oncogenic effects conferred by myristoylation arise, in part, from the tendency of the membrane-targeted form of the protein to reside in cholesterol-rich membrane microdomainsNone
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias. None
Dopamine Transporter-related reduction of extracellular dopamine levels appears to be selectively affecting the D2 receptor-mediated signaling pathway as evidenced by an increase in the basal phosphorylation state of Proto-Oncogene Proteins c-akt.None
Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter. None
CDC37 in concert with HSP90 plays an essential role in maintaining oncogenic protein kinase clients including ERBB2, CRAF, CDK4, CDK6, & phosphorylated AKT.None
Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. None
The prostaglandin E2 receptor, EP4 subunit genetic deficiency in macrophages suppresses the Pik3ap1 protein/Proto-Oncogene Proteins c-akt signaling pathway, reducing activation of bcl-associated Death protein, which results in increased apoptosis.None
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosisNone
Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. None
The role of PAK-1 in activation of MAP kinase cascade and oncogenic transformation by Akt. None
Phosphatidylinositol 4,5-bisphosphate-specific AKT1 is oncogenic. None