Sentence and cancer type
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SentenceCancertype
ERF is a ubiquitously expressed ets domain transcriptional repressor with tumor suppressor activity that is regulated by the Ras/Erk signaling pathway.None
data provide evidence that the oncogenicity of ERG is mediated, in part, by competition with ERF and they raise the larger question of whether other gain-of-function oncogenic transcription factors might also inactivate endogenous tumour suppressorsNone
ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation.None