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Cancertype
ERGdel could compromise the potentially oncogenic effect of wild-type ERG resulting in a negative effect on disease aggressiveness
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We examined the correlation of clinicopathological factors and prognosis with ERG and the TMPRSS2-ERG fusion oncogene and ERG expression as predictive markers--REVIEW}
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Authors demonstrate a novel role for BRD4 in the formation of oncogenic TMPRSS2-ERG fusions via its involvement in the NHEJ DNA repair pathway.
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Data show that overexpression of Erg oncogene protein (ERG) in the promotes resistance to combined phosphatidylinositol 3-kinases (PI3K) and androgen receptor (AR) pathway inhibition.
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Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2.
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The erg gene: a human gene related to the ets oncogene.
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