| Our findings point to a tumor suppressor role for ETS2 in human NSCLC pathogenesis through inhibition of the MET proto-oncogene. | lung, |
| Amplification of ETS2 oncogene in acute nonlymphoblastic leukemia with t(6;21;18). | leukemia, |
| The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy. | leukemia, |
| The product of the c-ets-1 proto-oncogene and the related Ets2 protein act as transcriptional activators of the long terminal repeat of human T cell leukemia virus HTLV-1. | leukemia, |
| Transcriptional regulation of miR-196b by ETS2 in gastric cancer cells. | gastric, |
| Expression of the human ETS-2 oncogene in normal fetal tissues and in the brain of a fetus with trisomy 21. | brain, |
| ets-1 and ets-2 proto-oncogene expression in human leukemia cells and cell lines. | leukemia, |
| Data suggest marked changes in DNA methylation occur at a single CpG site (CpG4) in promoter region of ESR1 as breast cancer cells become resistant to hormonal/aromatase inhibitor antineoplastic agents; this CpG region is completely conserved among species, suggesting that it acts as a methylation-sensitive ETS2 transcription factor binding site/response element. (ESR1 = estrogen receptor 1; ETS2 = ETS proto-oncogene 2) | breast, |
| ETS2 functions as an oncogene and plays a key role in the progression of hypopharyngeal cancer. | laryngeal, |
| Monoclonal antibodies specific to human ETS-2 oncoprotein: recognition of epitopes clustered on the B domain. | None |
| Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. | None |
| Positive and negative factors regulate the transcription of the ETS2 gene via an oncogene-responsive-like unit within the ETS2 promoter region. | None |
| Differential allelic distribution of V-ets erythroblastosis virus E26 oncogene homolog2 (ETS2) functional polymorphisms in different group of patients. | None |
| Squelching of ETS2 transactivation by POU5F1 silences the human chorionic gonadotropin CGA subunit gene in human choriocarcinoma and embryonic stem cells. | None |
| Involvement of V-Ets erythroblastosis virus E26 oncogene homolog 2 in regulation of transcription activity of MDR1 gene. | None |
| MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. | None |
| These results suggest an unappreciated role for ETS2 in fibroblasts in establishing an immune-suppressive microenvironment in response to oncogenic Kras(G12D) signaling during the initial stages of tumor development. | None |
| c-ets-2 protooncogene has mitogenic and oncogenic activity. | None |
| A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C. | None |
| Characterization and localization of the products of the human homologs of the v-ets oncogene. | None |