| ETV6 generally plays as tumor-suppressor gene in leukemia. | leukemia, |
| Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6 | prostate, |
| Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor. | None |
| TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL. | None |
| Data suggest that TEL exerts a tumor suppressive function through augmenting the p53 pathway. | None |
| The deleted segment on 12p contains several genes, among the tumor suppressor genes ETV6 and CDKN1B, which are frequently involved in 12p abnormalities in childhood ALL. | None |
| This cell line will be very useful in studying the different mechanisms by which alterations of ETV6 contribute to leukemogenesis and in testing the hypothesis that ETV6 might act as a tumor suppressor gene. | None |
| Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. | leukemia, |
| Immature CD34+CD19- progenitor/stem cells in TEL/AML1-positive acute lymphoblastic leukemia are genetically and functionally normal. | leukemia, |
| TEL-fusion oncogenic tyrosine kinases determine leukemic cells response to idarubicin. | leukemia, |
| The TEL/ARG leukemia oncogene promotes viability and hyperresponsiveness to hematopoietic growth factors. | leukemia, |
| The TCR gene rearrangements in childhood B-lineage acute lymphoblastic leukemia was associated with expression of TEL chimeric oncogene. | leukemia, |
| The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression. | leukemia, |
| ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex. | breast, |
| STAT3 mediates oncogenic addiction to TEL-AML1 in t(12;21) acute lymphoblastic leukemia. | leukemia, |
| RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia. | leukemia, |
| Molecular genetic studies on 167 pediatric ALL patients from different areas of Pakistan confirm a low frequency of the favorable prognosis fusion oncogene TEL-AML1 (t 12; 21) in underdeveloped countries of the region. | pediatric, |
| ETV6/ARG oncoprotein confers autonomous cell growth by enhancing c-Myc expression via signal transducer and activator of transcription 5 activation in the acute promyelocytic leukemia cell line HT93A. | leukemia, |
| The study shows a low representation of ETV6-RUNX1 fusion oncogenes among pediatric acute lymphoblastic leukemia patients from King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia. | leukemia,pediatric, |
| Nasopharyngeal carcinoma (NPC) super-enhancers with extraordinarily broad and high H3K27ac signals were identified, and they were linked to genes important for oncogenesis including ETV6. ETV6 was also highly expressed in NPC biopsies by immunohistochemistry | nasopharyngeal,laryngeal, |