Sentence and cancer type
Showing 1-13 of 13 items.
SentenceCancertype
FGFR2 is a transforming oncogene in human mammary epithelial cells when expressed to levels similar to that found in breast cancer cells with FGFR2 gene amplification.breast,
Despite the low incidence of FGFR2 mutations in ovarian cancer, the two FGFR2 mutations identified in ovarian tumors overlap with the oncogenic mutations previously identified in endometrial tumors.ovarian,endometrial,
FGFR2 has a dual role in the endometrium, by inhibiting cell proliferation in normal endometrium during the menstrual cycle, but acting as an oncogene in endometrial carcinoma.endometrial,
Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2. sarcoma,
HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for targeted therapies in gastric carcinoma. gastric,
FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26. None
Transforming potential of alternatively spliced variants of fibroblast growth factor receptor 2 in human mammary epithelial cells. None
The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects. None
FGFR2 and FGFR3 gain of function mutants might be facilitators for oncogenic transformation in medulloblastoma.None
The oncogenic nature of mutations observed in FGFR2 and FGFR3.None
FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma. None
Identification of Oncogenic and Drug-Sensitizing Mutations in the Extracellular Domain of FGFR2. None
This study reveals a direct binding event and characterizes the role of TRPA1 ankyrin repeats in regulating FGFR2-driven oncogenic process; a mechanism that is hindered by miRNA-142-3pNone