Sentence and cancer type
Showing 1-4 of 4 items.
SentenceCancertype
PLA2R1 plays a role in cancer as a tumor gene suppressor and is the major target antigen of auto-immune antibodies involved in idiopathic membranous nephropathy, a severe human kidney disease.[review]kidney,
Inactivating frameshift mutation of putative tumor suppressor genes PLA2R1 and SRPK1 in gastric and colorectal cancersgastric,colorectal,
Results identify PLA2R (phospholipase A2 receptor) as a potential new tumour suppressor gene crucial in the induction of cellular senescence through the activation of the p53 pathway.None
This review compiles recent data demonstrating an unexpected tumor suppressive role of PLA2R1 and outlines the future work needed to improve our knowledge of the functions of this gene in cancer.[review]None