| This study reveals functional and mechanistic links between miRNA-224 and the tumor suppressors PHLPP1 and PHLPP2 in the pathogenesis of colorectal cancer | colorectal, |
| Authors investigated the relationship between Usp12, PHLPP and PHLPPL tumour suppressors in the regulation of AR transcriptional activity in prostate cancer. | prostate, |
| miR-938 promotes colorectal cancer cell proliferation via targeting tumor suppressor PHLPP2 | colorectal, |
| miR493 acted as a onco-miR in prostate cancer cells and promoted cell proliferation via inhibiting tumor suppresser PHLPP2 expression and activating Akt signaling pathway. | prostate, |
| Transcription factor C/EBP-? induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells | None |
| DualLuciferase activity assay demonstrated that the tumor suppressor PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) was a target of miR125b, which inhibited PHLPP2 and directly bound to the 3_untranslated region of PHLPP2, resulting in elevated Akt signaling. | None |