Sentence and cancer type
Showing 1-11 of 11 items.
SentenceCancertype
USP22 exerts tumor-suppressive functions in colorectal cancer by decreasing mTOR activitycolorectal,
Ubiquitin Specific Peptidase 22 Regulates Histone H2B Mono-Ubiquitination and Exhibits Both Oncogenic and Tumor Suppressor Roles in CancerNone
Prognostic significance of USP22 as an oncogene in papillary thyroid carcinoma. thyroid,
USP22 acts as an oncogene by regulating the stability of cyclooxygenase-2 in non-small cell lung cancer. lung,
Oncogenic USP22 supports gastric cancer growth and metastasis by activating c-Myc/NAMPT/SIRT1-dependent FOXO1 and YAP signaling.gastric,
USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair.prostate,
USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway. None
USP22 may act as an oncogene in CRC as it positively regulates cell cycle via both BMI-1-mediated INK4a/ARF pathway and Akt signaling pathway.None
USP22 regulates oncogenic signaling pathways to drive lethal cancer progression. None
findings of the present study suggest a potential mechanism underlying the oncogenic role of USP22 mediated by the modulation of the stability and activity of COX-2None
USP22 deficiency leads to leukemogenesis through oncogenic Kras activation by a PU.1-dependent mechanism.None