| A novel perspective regarding circRNA function in physiological and pathological processes: specifically, SHPRH-146aa generated from overlapping genetic codes of circ-SHPRH is a tumor suppressor in human glioblastoma. | glioblastoma, |
| SHPRH maps to 6q24 and is a possible candidate for the tumor suppressor gene reported from that region. | None |
| We report that a putative tumor suppressor gene, SHPRH, is a human orthologue of yeast RAD5.The yRad5/SHPRH-dependent pathway is a conserved and fundamental DNA repair mechanism that protects the genome from genotoxic stress. | None |