| CHD5 is the strongest candidate tumor suppressor gene that is deleted from 1p36.31 in neuroblastomas, and inactivation of the second allele may occur by an epigenetic mechanism. | neuroblastoma, |
| study demonstrated the existence of somatic mutations and methylation of CHD5 in primary epithelial ovarian cancers; CHD5 may play a role as a tumor suppressor gene in ovarian cancer | ovarian, |
| CHD5 is a tumor suppressor gene epigenetically down-regulated in gastric cancer | gastric, |
| data suggest that CHD5 is a tumor suppressor gene that is epigenetically downregulated in laryngeal squamous cell carcinoma. | laryngeal, |
| CHD5 is a potential tumor suppressor gene that is inactivated via an epigenetic mechanism in lung cancer. | lung, |
| CHD5 might act as a tumor suppressor in glioma | glioma, |
| These findings provide insights into the regulatory role of CHD5 during neurogenesis and suggest how inactivation of this candidate tumor suppressor might contribute to neuroblastoma. | neuroblastoma, |
| CHD5 is a potential tumour suppressor gene epigenetically silenced in hepatocellular carcinoma. | liver, |
| Influence of colorectal cancer tumor suppressor gene CHD5 methylation on its clinical and pathological characteristics | colorectal, |
| Data show that chromodomain helicase DNA binding protein 5 (CHD5) acted as a functional tumor suppressor and was frequently silenced by promoter CpG methylation in renal cell carcinoma (RCC). | kidney, |
| CHD5 may act as a tumor suppressor gene in NSCLC. | lung, |
| Study demonstrates that Chd5 functions as a tumor suppressor in vivo and implicates deletion of CHD5 in human cancer. | None |
| A recent functional study identified chromodomain helicase DNA-binding protein 5 (CHD5) as a novel tumor suppressor mapping to 1p36. [REVIEW] | None |
| The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping. | None |
| Study shows that CHD5 is a Nucleosome remodeling and deacetylase complex-associated transcriptional repressor and identifies WEE1 as one of the CHD5-regulated genes that may link CHD5 to tumor suppression. | None |