| The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis. | None |
| Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor. | None |
| MicroRNA-31 regulated by the extracellular regulated kinase is involved in vascular smooth muscle cell growth via large tumor suppressor homolog 2. | None |
| At low cell density, overexpression of the Hippo pathway kinase large tumor suppressor 2 (Lats2) inhibited c-Abl activity. | None |
| results reported here further support that LATS1/2 act normally as tumor suppressors and loss of their functions contributes to human cancer development | None |
| PVT1 recruits EZH2 to the large tumor suppressor kinase 2 (LATS2) promoter and represses LATS2 transcription. | None |
| Study demonstrates that, in 3 different murine syngeneic tumor models (B16, SCC7, and 4T1), loss of the Hippo pathway kinases LATS1/2 (large tumor suppressor 1 and 2) in tumor cells inhibits tumor growth; data indicate a new paradigm for how tumor immunogenicity is regulated through the Hippo signaling pathway in tumor cells. | None |
| Deubiquitylase USP9X suppresses tumorigenesis by stabilizing large tumor suppressor kinase 2 (LATS2) in the Hippo pathway | None |
| Large tumor suppressor 2, LATS2, activates JNK in a kinase-independent mechanism through ASK1 | None |