Sentence and cancer type
Showing 1-12 of 12 items.
SentenceCancertype
Results demonstrate that GFI1 acts as a tumor suppressor gene in colorectal cancer, where deficiency of Gfi1 promotes malignancy in the colon.colorectal,
Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells. prostate,kidney,
The oncogenic role of the transcription factor GFI1 in gastric cancer.GSK3B controls GFI1 expression via phosphorylation of Serine 94 and Serine 98 sites, which leads to SCFFBXW7-mediated polyubiquitination and proteasome degradation.gastric,
Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis. lymphoma,
A house fly gene homologous to the zinc finger proto-oncogene Gfi-1. None
Targets of the transcriptional repressor oncoprotein Gfi-1. None
Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2None
Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2. None
findings highlight the role of epigenetics in the regulation of development and oncogenesis by Gfi1None
results, supported by evidence from mouse models, identify GFI1 and GFI1B as prominent medulloblastoma oncogenes and implicate _enhancer hijacking_ as an efficient mechanism driving oncogene activation in a childhood cancerNone
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. None
The C. elegans gene pag-3 is homologous to the zinc finger proto-oncogene gfi-1. None