| Cx43 was found to colocalize with beta-catenin and negatively regulate the Wnt signaling pathway, and expression of Cx43 was associated with increased levels of apoptosis; data indicate that Cx43 is a colorectal cancer tumor suppressor protein that predicts clinical outcome | colorectal, |
| loss of Cx43 may be an important event in colon carcinogenesis and tumor progression, providing significant insights about the tumor suppressive properties of the Cx43 and its potential as a diagnostic marker for colon cancer. | colorectal, |
| Connexin 43, breast cancer tumor suppressor: Missed connections? | breast, |
| Cx43 plays a role as a tumor suppressor, however, no definite correlation was found between Cx43 and cell migration and invasion. | None |
| The significantly higher Cx43 staining in malignant melanoma when compared with nevi suggests an oncogenic role for this protein in melanocytic tumor progression | skin, |