| PELP1 exhibits an oncogenic function in colorectal cancer through c-Src upregulation. | colorectal, |
| Data suggest that PELP1 is a potential oncogene, that its expression is deregulated during cancer progression, and that PELP1 may play a role in oncogenesis. | None |
| Cyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1. | None |
| Regulation of rDNA transcription by proto-oncogene PELP1. | None |
| proto-oncogene PELP1 plays a vital role in rDNA transcription | None |
| Inhibition of CARM1 decreases PELP1 oncogenic activity. | None |
| PELP1 oncogenic functions involve alternative splicing via PRMT6. | None |
| our data identified the PELP1-mTOR axis as a novel component of PELP1 oncogenic functions and suggest that mTOR inhibitor(s) will be effective chemotherapeutic agents for downregulating PELP1 oncogenic functions. | None |