| Sonic hedgehog-glioma associated oncogene homolog 1 signaling enhances drug resistance in CD44(+)/Musashi-1(+) gastric cancer stem cells. | gastric,glioma, |
| Our studies demonstrate an important role for smoothened and glioma-associated oncogene homology-1 in gastric cancer and suggest inhibition of hedgehog pathway as a novel and potent strategy to treat gastric cancer patients | gastric,glioma, |
| Data show that miR-150 inhibits glioma-associated oncogene homolog 1 (Gli1) expression via targeting 3_-UTR of Gli1 gene. | glioma, |
| Histone deacetylase 6 (HDAC6) inhibition enhanced glioma stem cells (GSCs) radiosensitivity via inactivating sonic hedgehog protein (SHH)/glioma-associated oncogene homolog 1 (Gli1) pathway. | glioma, |
| Active serum response factor (SRF) along with its coactivator megakaryoblastic leukemia 1 (MKL1) binds DNA near hedgehog target genes and forms a previously unknown protein complex with the hedgehog transcription factor glioma-associated oncogene family zinc finger-1 (GLI1), causing amplification of GLI1 transcriptional activity. | leukemia,glioma, |
| The authors report that truncated glioma-associated oncogene homolog 1 (tGLI1) is a tumor-specific transcription factor that facilitates glioblastoma growth, is enriched in the mesenchymal subtype of glioblastoma and glioma stem cells (GSC), and promotes mesenchymal GSC by upregulating transcription of CD44. | glioblastoma,glioma, |
| Spheroid cultures increased expression of the cancer stem cell marker glioma-associated oncogene homolog 1 (Gli1) | glioma, |
| LINC01093 directly binds insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1), interfering with interaction between IGF2BP1 and glioma-associated oncogene homolog 1 (GLI1) mRNA. The result is degradation of GLI1 mRNA, further affecting expression of GLI1 downstream molecules involved in HCC progression. | liver,glioma, |
| Clinical Significance of Glioma-associated Oncogene 1 Expression in Patients With Locally Advanced Gastric Cancer Administered Adjuvant Chemotherapy With S-1 After Curative Surgery. | gastric,glioma, |
| Letters to the editor: identification of polymorphic variants of the GLI1 oncogene. | None |
| Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5 untranslated regions. | None |
| Are keloids really gli-loids?: High-level expression of gli-1 oncogene in keloids. | None |
| Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas. | None |
| Gli-1 oncogene: the key to keloidogenesis?. | None |
| The EWS/FLI1 oncogenic transcription factor deregulates GLI1. | None |
| GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein. | None |
| Our data reveal a novel mechanism of regulation of Gli1 stability and function, which influences Hedgehog/Gli1 oncogenic potential. | None |
| The data support a model in which the metastatic transition involves the acquisition or enhancement of a more primitive embryonic stem-like phenotype, and the downregulation of the early WNT-TCF programme, driven by oncogene-regulated high GLI1 activity. | None |
| Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation. | None |
| Data suggest that blocking Gli transactivation, an important control point of multiple oncogenic pathways, may be an effective anticancer strategy. | None |